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Reducing climate change and global warming

Professor Ken Naitoh from Waseda University in Japan charts a particular interdisciplinary carbon-neutral approach for reducing climate change and global warming that he believes will lead to a more peaceful world.

MAGL inhibition: A novel treatment option for combating inflammatory disease?

Pharma researchers Uwe Grether and Julie Blaising from F. Hoffmann-La Roche Ltd. highlight the vast therapeutic potential of MAGL inhibition for central and peripheral diseases.

CH-Bioforce strives for a cleaner world with unique bioforsense technology

In this interview, Petri Tolonen, CEO of CH-Bioforce, sheds light on the environmental benefits of Bioforsense technology.
Figure 1. Schematic of the pioneering CERN experiments showing that proton-proton collisions produce neutrinos (1,2) (top) and interpretation according to RLM of composite particles (bottom).(4-6)

Neutrino production in proton-proton collisions supports the rotating lepton model

Direct observation of neutrino production in proton-proton (pp) collisions at CERN LHC lend strong support to the Rotating Lepton Model, Constantinos G. Vayenas(1), Dionysios Tsousis(1,2) and Eftyhia Martino1 ((1)University of Patras, (2)Stanford University) tell us.

Microfluidic microbial bioreactors: How studying microbes at the microscale can help empower microbiology

Long before the existence of microbes was known, humans were unknowingly harnessing their power through practices such as brewing, bread leavening, or cheesemaking. These processes extended the shelf life of food, enhanced its nutritional value, and significantly contributed to the advancement of industry and civilization.
Figure 1. Elements of the operational RNA code in the tRNA acceptor stem. A. Bases in the tRNA acceptor stem encode two aspects of amino acid physical chemistry—size and polarity—that determine protein folding. B. Acceptor stem bases preceded the anticodon stem-loop and code other properties. C. The oldest parts of Class I and II AARS could already discriminate between both amino acid and RNA substrates (6) .

tRNA: The operational RNA code and protein folding

Charles W. Carter, Jr., from the Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, relates molecular recognition used in genetic coding to structures of aminoacyl-tRNA synthetases and their cognate tRNAs.

Digital Life Norway (DLN) Initiative to foster and boost transdisciplinary biotechnology research and innovation

Meeting the rapid developments in biotechnology by fostering transdisciplinarity, including digitalisation and big data, to create convergence for innovation in a virtual centre.
Figure 1: Early research at Purdue University in the Webster lab that led to the formation of Nanovis, which now has over 3,000 FortiFixTM pedicle screws inserted in humans with no cases of implant failure, according to the Maude database. The industry standard of pedicle screw failures lies between 5 – 10% depending on the data assessed.

Opinion: Do universities help or hurt innovation?

Do Universities help or hurt innovation? Find out in this 25-year academic entrepreneur’s anecdotal perspective of starting companies and developing implants. Thomas J. Webster shares his opinion here.
Group of bacteria such as Escherichia coli, Helicobacter pylori or salmonella 3D rendering illustration on blue background. Microbiology, medical, bacteriology, biology, science, healthcare, medicine, infection concepts.

Microbe development for the biomanufacturing age

Joe Price, Dr Kang Lan Tee & Prof Tuck Seng Wong, explore adopting a holistic approach to microbe development for the age of biomanufacturing.
Shot of a young scientist using a microscope while conducting research in a laboratory

Responsible and ethical conduct of research: Principles to uphold

Greg M. Swain, Professor of Chemistry at Michigan State University, emphasizes the importance of responsible and ethical conduct of research (RECR) in scientific progress.
Magnet levitating above a high-temperature superconductor

Superconductivity and related macroscopic quantum phenomena

John H. Miller, Jr., from the University of Houston, Dept. of Physics and Texas Center for Superconductivity, walks us through superconductivity and related macroscopic quantum phenomena.
circular economy, economy, linear economy, economy

Purple non-sulfur bacteria and the circular economy

Arpita Bose, Associate Professor at Washington University in St. Louis, discusses the potential of microbial solutions in supporting sustainable and environmentally responsible alternatives to the traditional linear economy.
A group of antibiotic pill capsules fallling. Healthcare and medical 3D illustration background.

Drug repositioning using multiple gene expression profiles

Chuo University’s Professor Y-h. Taguchi places focus on drug repositioning using multiple gene expression profiles
Aerial View of Beijing Traffic Jam

Using lotteries instead of auctioning is both inefficient and inequality-creating

Yew-Kwang Ng, Emeritus Professor in the Department of Economics at Monash University, compares the use of the lottery and auctioning to allocate scarce goods.
A financial data analysis graph. Selective focus. Horizontal composition with copy space.

Towards generalised pairs trading strategies through AI

Here, we learn about Professor Chien-Feng Huang’s interdisciplinary research at the National University of Kaohsiung in Taiwan, concerning the move towards generalised pairs trading strategies through artificial intelligence.
Figure 1. (a) High-resolution transmission electron microscopy image of UNCDTM coating, showing 3-5 nm grains; (b) Schematic of Si microchip (artificial retina)-left/cross-section scanning electron microscopy (SEM-top right) image of UNCD-encapsulated microchip and electrodes (bottom) made of Si tips coated with unique electrically conductive N atoms-doped N-UNCD coating. Injecting electrons in ganglion cells, transferring to the brain to produce an image; (c) Cross-section SEM image of UNCD-coated DI; (d) X-ray image of UNCD- coated DI (upper left) and UNCD-coated DI in maxillary bone of one of 51 patients implanted with UNCD-coated DI in clinical trials (2018 to present); (e) Schematics of artificial hip (top)/knee (bottom) to be coated with UNCDTM; (f) Water drop contact angle (178 ̊) on CF4 plasma processed UNCDTM surface, showing highest super-hydrophobicity of any known biomaterial, inhibiting blood cells adhesion on stent’s surface (Fig. 1(g))/heart valve’s surface (Fig. 1 (h)), eliminating thrombus formation. (5)

Ultrananocrystalline diamond (UNCD™) coating for new-generation implantable medical devices/prostheses

In this materials science piece, Orlando Auciello, describes the development of a unique multifunctional/best biocompatible ultrananocrystalline diamond (UNCDTM) coating for new-generation implantable medical devices and prostheses.
Image: © NSF/LIGO/Sonoma State University/A. Simonnet

What remains when two neutron stars collide?

Distinguished Professor Susan M. Scott and Dr Karl Wette from the Australian National University examine what remains when two neutron stars collide in this exciting gravitational astrophysics focus.
A scientist using a pipette with a microtiter plate and a petri dish

AI and modern experimental biology: A historical perspective

Ute Deichmann, Director of the Jacques Loeb Centre for the History and Philosophy of the Life Sciences at Ben-Gurion University of the Negev, discusses the adoption and limitations of Artificial Intelligence within modern experimental biology.
Tumor microenvironment concept with cancer cells, T-Cells, nanoparticles, cancer associated fibroblast layer of tumor microenvironment normal cells, molecules, and blood vessels 3d rendering

Understanding T lymphocytes inner workings to harness therapeutic potential

Leslie J. Berg, PhD from the University of Colorado, Anschutz School of Medicine, sheds light on understanding the inner workings of T lymphocytes to harness their therapeutic potential.

Data management plans as a tool for making data fair

Andy Götz (ESRF Data Manager and PaNOSC Coordinator), explores if and how Data Management Plans (DMPs) are essential for making data FAIR.
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