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The next chapter in regenerative medicine for osteoarthritis: From real-world evidence to regulatory shifts
Osteoarthritis (OA) remains one of the leading causes of disability worldwide, yet the therapeutic landscape is evolving faster than ever.
Personalizing wellbeing interventions in the digital era
Troy W. Norris’ WellBalance Institute is advancing the science of positive psychology and wellbeing to create personalized plans and practical tools to build happy, flourishing, and resilient lives, workplaces, and communities
Rational use of psychotropic medications in youth
This article examines a holistic approach to youth mental health care and discusses the concept of ‘deprescribing’ as a systematic method for assessing the necessity and risks associated with the continued use of medication.
Revolutionising global vaccine access: The case for Stablepharma’s fridge-free vaccine technology
Stablepharma is focused on improving global vaccine access with its leading candidate, SPVX02. Here, they discuss the challenges of vaccine development and distribution, and highlight how their platform could transform accessibility through fridge-free vaccines.
The oncoming tsunami of RNA therapeutics
Alan Herbert, Founder and President of InsideOutBio, discusses the significant advancements in RNA therapeutics, highlighting their role in supporting public health and their transformative potential in modern medicine, particularly for addressing genetic conditions and cancer.
Prevention of eating disorders with single session interventions: Hype or promise?
Is reducing the risk of eating disorders with single session interventions a hype or a promise? Tracey Wade at the Flinders University Institute for Mental Health and Wellbeing investigates.
Enabling preventive medicine and improving patient care via aptamer-based molecular monitors
As health systems put greater focus on preventive, personalized care, Netzahualcóyotl Arroyo-Currás tells us about the broad benefits of Continuous Molecular Monitors (CMMs) in providing insights into biomolecular markers that facilitate early disease detection.
Protecting infants from brain damage: A focus on HIE
Lee J. Martin, PhD from Johns Hopkins University School of Medicine, discusses the pathology of infant hypoxic-ischemic encephalopathy (HIE), and the research he and his team are conducting to understand cell death mechanisms related to HIE and therefore identify new therapies.
Deconstructing misconceptions: The relevance of androgens for human health
Alexandra Cara and Carol F. Elias from the University of Michigan Medical School provide insights into the critical role of androgens in human health, including their vital roles throughout various life stages.
What makes GLP1 receptor agonist drugs so effective for obesity?
Michael W. Schwartz, MD, discusses the effectiveness of GLP1 receptor agonist drugs, such as semaglutide and tirzepatide, in treating obesity as well as the role of gut-brain signaling in maintaining energy homeostasis.
Empowering the disempowered: Remote pregnancy monitoring for hard-to-reach populations
Tobias R. Kollmann, Professor at Dalhousie University, and Nima Aghaeepour, Professor at Stanford University, examine remote pregnancy monitoring for hard-to-reach populations.
Prioritizing skeletal muscle health for successful aging
Kevin A. Murach, Ph.D. at the University of Arkansas, talks us through prioritizing skeletal muscle health for successful aging, beginning with a primer on skeletal muscle aging.
Protection from occupational heat stress amid rising global temperatures
Prof Luana Main emphasises that as extreme heat events become more frequent due to rising global temperatures, immediate action is essential to protect workers through evidence-based and context-specific risk mitigation strategies and solutions.
Leadless pacemakers: Minimizing infections of cardiac pacemakers and defibrillators
As the population ages, concerns about infections related to cardiac implantable electronic devices (CIEDs) are increasing. This article explores the risk factors and proposes potential solutions to improve the safety of cardiac devices.
Compassion starts within: Mental health and wellbeing for healthcare professionals
With burnout being common among healthcare professionals, Dr Dianne Wepa and Tanya Levin discuss practical strategies for supporting the mental health of healthcare workers.
Single chromosome sequencing with Haplomic Technologies
Explore single chromosome sequencing with Haplomic Technologies, starting with some background and corporate history.
Unravelling NASH and insulin resistance: Insights from the department of human health and nutritional...
Open Access Government sits down with a researcher from the Department of Human Health and Nutritional Sciences to discuss their groundbreaking work on nonalcoholic steatohepatitis (NASH) and insulin resistance. Their research delves into the molecular underpinnings of these increasingly prevalent conditions, offering new avenues for understanding, prevention, and treatment.
The NAD+ stack, optimized: A multi-target strategy to support healthy aging
Research has identified key mechanisms driving aging and actionable targets for promoting longevity. A promising strategy is to preserve the cell’s ability to produce energy, repair DNA, and stress resilience, with nicotinamide adenine dinucleotide (NAD+) playing a central role. Here, Dr. Rebecca Crews presents a multi-target approach to support healthy aging.
Asbestos: Early immune responses
Ujjwal Adhikari, Kinta Serve, and Jean Pfau explain how asbestos exposure negatively affects the body’s immune response and repair mechanisms, particularly through macrophage dysfunction. They emphasize that gaining a better understanding of cellular responses to inhaled particles could help researchers discover new therapeutic strategies for addressing environmentally induced conditions.
Ocular nutrition for a digital generation
Effective nutritional solutions to support healthy vision in children affected by Computer Vision Syndrome (CVS). Discover how healthcare professionals and policymakers can promote eye health and reduce the impact of screen time on kids.