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The doctor's hands touch the burn on the man's shoulders, close-up. Allergy to the sun, dermatological diseases

Living with rare genetic disorders: Challenges of EPP and XLP

Kirstine Juhl Belongie discusses the impact, symptoms, and possible treatments related to EPP and XLP, two debilitating disorders that cause extreme pain following exposure to sunlight.

The role of host condition and environment on infection outcome

Brian P. Lazzaro from Cornell University discusses his research on the factors influencing immune response and infection outcome, drawing on powerful experimental systems, such as Drosophila melanogaster as a model host, to gain a deeper understanding of foundational biological processes.
Team of Medical Research Scientists Conduct Experiments with Help of Microscope, Test Tubes, Micropipette and Desktop Computer. Modern Biological Applied Science Laboratory with Diverse Colleagues.

Exposomics: A shift in biomedical research with potential to improve human health

Recent advances in exposomics offer an exciting opportunity to comprehensively catalog human exposures and link them to biological responses determining health and disease. Pamela J. Lein, Ph.D. from the University of California, tells us more.
Blurred shot of a team of doctors standing together in a hospital

Five tips to implement self-compassion for healthcare workers

Self-compassion is not a cure-all for systemic challenges within the health system, but it can enhance resilience, social support, and self-efficacy among healthcare workers, ultimately improving their quality of life in the workforce.
An adorable photo of a three (3) month old baby girl sleeping on her mother's chest. Her mother is looking down at her baby daughter with a soft smile on her face.

Solutions for better sleep

Dr Lianne Tomfohr-Madsen highlights sleep health equity research to inform best practices and policies to improve the sleep of all Canadians.
3d illustration of clostridium bacteria

An ancient therapy modernized for Clostridioides Difficile therapy

Clostridioides difficile is a type of bacteria that often affects people who have been taking antibiotics. Glenn S. Tillotson of GST Micro LLC explains how live biotherapeutic products have shown promise as a safe and effective treatment to help restore the normal gut microbiome.
abstract motion-blurred view from the front of a train in Tokio, Japan

Understanding electromagnetic hypersensitivity (EHS)

Electromagnetic hypersensitivity: Michael Bevington, Chair of Trustees at Electrosensitivity UK, explains the health risks associated with exposure to radiofrequency radiation and electromagnetic fields and why more robust action is needed to protect public health.
Close-up of young woman's hand holding birth control pills

Hormonal contraceptive designs and women’s mental health – Timing is of the essence!

Professor Belinda Pletzer from the Centre for Cognitive Neuroscience at Paris Lodron University of Salzburg explores the physical and psychological symptoms of a pill pause. She advocates for hormonal contraceptive designs that focus on women’s health needs instead of socio-cultural misconceptions about menstrual bleeding.
Figure. G-quadruplexes cycle between a four-stranded fold and the Watson and Crick B-DNA conformation. Nature uses many different tissue-specific proteins to drive the cycle. Therapeutic approaches to targeting G-quadruplexes include drugs, such as PROTACS that send them to garbage, small molecules that either promote or disrupt their formation, or small RNAs that target the DNA or RNAs sequences that form them.

Targeting the most complex flipon of them all in the fight against cancers

In this article, Alan Herbert, the Founder, and President of InsideOutBio, guides us through targeting the most complex flipon of them all in the fight against cancers.

Asbestos, the pleural cavity, and autoimmune disease

Jean C. Pfau, Ph.D. from the Center for Asbestos-Related Disease and Kinta Serve from Idaho State University, provide their perspective on asbestos, the pleural cavity, and autoimmune disease.
image from the International Self-care Foundation Limited

Mental health and self-care: A comprehensive guide

This short guide explores the importance of self-care for good mental health and provides practical tips for implementing self-care strategies.

Data integration: A key to understanding the biological basis of mental disorders

ses two key advancements in genome-wide association studies (GWAS) and gene expression data to better understand the biological basis of mental disorders.

MMPC-live: Accessible resources for phenotyping of live mouse models of diabetes and obesity

Professor Carol F. Elias, from the University of Michigan’s Department of Molecular & Integrative Physiology, discusses key research opportunities enabled by the NIDDK Mouse Metabolic Phenotyping Center in live models – MMPC-Live.
senior woman at an appointment with a chiropractor

Joint manipulation, a hands-on therapeutic technique

Rob Sillevis from the Marieb College of Health and Human Services explores joint manipulation, a hands-on therapeutic technique designed to relieve pain, improve mobility, restore joint function, and enhance patient functionality.
Figure 1: Use of Single Session Intervention (SSI) before people start treatment for an eating disorder (SSIs were modified from those created by Schleider) (11)

Early intervention for eating disorders

Tracey Wade, Matthew Flinders Distinguished Professor, provides an insightful examination of the significance of brief early interventions in the treatment of eating disorders.
Negative emotion image. Person head shaped paper on black torn paper background.

Suicidal thoughts and actions: We need a new model

Konrad Michel, MD, Psychiatrist from the University of Bern, Switzerland, discusses the clinical approach to suicidal patients, providing a new look at a human phenomenon.
Figure 1. photo of a peripapillary intrachoroidal cavitation. The crescent-shaped atrophic area (red star), at the border of the optic nerve head (black star), called myopic conus, is alone in (A). It presents a circumscribed, yellow-orange lesion (white star) at its outer border in (B), corresponding to the peripapillary intrachoroidal cavitation. Note: Figures 1 and 2 are reprinted from Peripapillary Intrachoroidal Cavitation. Adèle Ehongo et al. ‘J. Clin. Med. 2023, 12, 4712’ Originally published by and used with permission from MDPI.

Spotting peripapillary intra-choroidal cavitation using OCT

Adèle Ehongo explores the potential of optical coherence tomography for diagnosing peripapillary intra-choroidal cavitation in myopic eyes.
Novel conjugate vaccines are generated by attaching various immune agonists to Chlamydia antigens using cell-free protein synthesis and click-chemistry. These vaccines are then tested in pre- clinical animal models for immunogenicity and efficacy. The top candidate(s) will progress to phase 1 clinical trials to determine safety and effectiveness against genital and ocular Chlamydia infections.

Advancing vaccine development for chlamydia

Genital Chlamydia trachomatis infection is a significant public health burden; Professor of Pediatrics and Microbiology and Immunology, Toni Darville, discusses the potential efficacy of CPAF-adjuvanted vaccines in mitigating the spread and impact of the infection.
Hands holding heart anatomy, organ donor, cardiac heart cancer, health care hospital service concept

The future of personalised cardiovascular disease detection and monitoring

Professor Allan Lawrie from Imperial College London, discusses the future of personalised cardiovascular disease detection and monitoring, including comment on wearable technology and AI.

E. coli genomes, big data, and messy biology

Here, David Ussery from the Department of BioMedical Informatics, UAMS, details E. coli genome diversity, big data, and messy biology. New methods, we discover, allow for the comparison of millions of bacterial genomes in a few days and the confident assignment of taxonomic clusters.

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