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The challenge of determining the health risks of low-dose chemical exposures

Rebecca J. Wilson and Pamela J. Lein, explore whether the dose makes the poison or not. Here, they discuss the challenges of determining health risks associated with low-dose chemical exposures.

Lives and money: Understanding the true cost of sepsis in Canada

Kali Barrett, Victoria Chechulina, and Fatima Sheikh discuss the economic burden of sepsis in Canada and the economic rationale for implementing coordinated, national strategies to combat this often-overlooked disease.
Figure 1: After controlling for cochlear health (assessed via RW-ECochG-TR), our data reveal that a short lateral wall electrode is linked to poorer CI performance when residual hearing is not preserved. Conversely, when a short lateral wall electrode is used, and residual hearing is preserved – enabling the use of electro-acoustic stimulation (EAS) – patients achieve excellent performance, whereas loss of residual hearing leads to significant underperformance.

Optimizing outcomes: The role of surgical technique and intraoperative factors in cochlear implant performance

Variability in cochlear implant performance remains a significant challenge for clinicians and patients. Contributors from Washington University School of Medicine investigate how surgical techniques and intraoperative adjustments can be refined to further optimize cochlear implant outcomes.
Worm nodules containing Onchocerca volvulus, the filarial species causing river blindness if not treated, on the head of a 5 year-old boy

Novel treatments offer hope for neglected tropical diseases

This interview with Professors Achim Hoerauf and Marc Hübner explores their groundbreaking work, focusing on the development of novel drugs and the importance of collaborative partnerships in tackling these devastating diseases.
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Microbiomes should be incorporated into The One Health Joint Plan of Action

The One Health Joint Plan of Action was created by major international organizations to tackle global health issues related to human, animal, plant, and environmental health. This article emphasizes the importance of integrating microbiomes into this framework to enhance health systems and prevention strategies.
Figure 1. The 5C model of student engagement in QR. Critical thinking is the heart of QR. QR Competencies and student Collaboration help students connect real-world Contexts to mathematical and statistical Concepts to make decisions about meaningful personal and professional issues.

Quantitative reasoning in higher education: The 5C Model

Quantitative reasoning enhances and lengthens lives. Professor Gregory Foley of Ohio University discusses how his team is improving QR instruction in U.S. higher education.
Medical Hospital Research Laboratory: Caucasian Male Neurosurgeon Looking At TV Screen With Brain MRI Scans Of Patient, Analyzing, Preparing For Complicated Neurosurgery, Wearing Surgical Gown.

Ultrasound neuromodulation for treatment-resistant depression: A case for deep brain stimulation

Tiago Costa from Delft University of Technology discusses why ultrasound neuromodulation has significant potential to transform the treatment of depression.
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Identifying potential exercise mediators

Dr Robert Wessells and his team at Wayne State University are researching exercise mediators and mimetics in fruit flies (Drosophila melanogaster) to explore how to provide the benefits of exercise to individuals who are unable to access it. Here, he shares what he has discovered during his research.

Novel imaging platform for early and precise cancer diagnosis

Regina Gumenyuk, Adjunct Professor at Tampere University, is exploring a novel imaging platform for early and precise cancer diagnosis. Read more about this exciting innovation here.

Common data elements to advance ME/CFS research

Standardizing data collection in ME/CFS research through Common Data Elements is a crucial step toward improving diagnosis, advancing treatments, and fostering collaboration across studies to accelerate progress in understanding this complex disease.
Old roofing slate in a pile. Asbestos, harmful to humans and the environment. Close up.

Amphibole asbestos as a public health risk in 2025: Autoimmune disease

Despite efforts to minimize exposure, deaths from asbestos-related diseases remain high. A recent review emphasized the importance of evaluating different mineral groups and pointed out that exposure to amphibole asbestos is linked to higher rates of autoimmune diseases. Jean C. Pfau and Brenda J. Buck discuss the urgent need to address this public health risk more effectively.
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Mental health research: The healing power of indigenous drumming

Gilles Comeau, Senior Scientist at the University of Ottawa, Institute of Mental Health Research at The Royal, explores the healing power of Indigenous drumming Drumming...
Woman alone in blue space, surreal painting, lonely people, loneliness artwork, hope and dream concept illustration, modern background

Consideration of key issues in positioning early intervention for eating disorders

Tracey Wade from the Flinders University Institute for Mental Health and Wellbeing outlines several key issues to consider in developing successful early intervention approaches for people with disordered eating and who are at risk of developing an eating disorder.
abs Bacteria concept - 3d rendered microbiology image. Medical research, health-care concept.

Bioinformatics into TB surveillance: A new approach to an ancient foe

David Ussery, a Professor in the Department of BioMedical Informatics at UAMS, and his Ph.D. student Brian Delavan discuss bioinformatics into TB surveillance, presenting a new approach to tackling this ancient foe.
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Process intensification: A game changer for the pharma market

Deborah McElhone, Head of Sustainability (Pharma) from CPI, argues that process intensification is a game changer for the pharma market.
Close-up of a loving owner scratching her adorable cat's neck on a living room floor at home

Feline coronavirus and feline infectious peritonitis (FIP) – Russian roulette for your pet

Utilising Machine Learning on clinical datasets could help to crack the enigma of feline infectious peritonitis diagnosis.

Personalized medicine in oncology: Small molecule inhibitors, biologics and immunotherapies

Priya Hays, PhD, CEO of Hays Documentation Specialists, discusses innovations and advancements in the development and evaluation of personalized cancer therapies.
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Stem cell exhaustion and its role in healthy aging

Scientist Sarallah Rezazadeh from the Icahn School of Medicine explores the molecular mechanisms behind adult stem cells as we age.
Figure 1. Landmarks of the peripapillary intrachoroidal cavitation (PICC). LC = lamina cribrosa. BM = Bruch’s membrane (dashed red arrow). SF = scleral flange, the sclera between the dura and the pia mater. D = dura mater. PICC (red star) is in front of the subarachnoid space (yellow star). It is a suprachoroidal detachment. It is suggested to be promoted by a direct traction force (blue arrow) of the dura mater during eye movements. A tangential component of this traction force squeezes the choroid at the end of the posterior outpouching (red arrowheads). The device used is the Spectral Domain OCT Spectralis® HRA-OCT, model S3300 (Heidelberg Engineering GmbH, Heidelberg Germany). Note: Reprinted from Peripapillary Intrachoroidal Cavitation. Adèle Ehongo et al. ‘J. Clin. Med. 2023, 12, 4712’ Originally published by and used with permission from MDPI.

Understanding the link between PICC and myopic complications

Dr Adèle Ehongo discusses the pathogenesis of peripapillary intra-choroidal cavitation and its implications for myopic complications.
Smoke Structure indoors

Prenatal cannabis exposure and its lasting impact on memory

Professors Miranda Reed from Auburn University and Vishnu Suppiramaniam from Kennesaw State University have studied how prenatal cannabis exposure affects brain development and cognitive functions, including memory.

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