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Cancer in the blood outbreak and treatment for malignant cells in a human body caused by carcinogens and genetics with a cancerous cell as an immunotherapy and leukemia or lymphoma symbol and medical therapy as a 3D render.

A novel approach to cancer chemotherapy

Richard F. Ludueña, Professor Emeritus at the University of Texas Health San Antonio, discusses his innovative approach to cancer chemotherapy, which could significantly enhance its effectiveness.

Fuelling the global supply of medical radioisotopes for cancer care

European research reactors play a crucial role in producing medical radioisotopes using nuclear fuel and are transitioning to Low Enriched Uranium (LEU) to meet non-proliferation commitments and global demand. Jared Wight tells us how he and his colleagues are working to ensure a smooth conversion to LEU fuels.

Empowering voices: Breaking mental health stigma

John Hoey and Mary Cannon from Department of Psychiatry, RCSI University of Medicine and Health Sciences, Dublin, Ireland, share their research around breaking mental health stigma to empower voices.
medical student with mentor prescribing ward medicines

A call to action: Supporting our nursing workforce through improved transition to practice

Dr. Kathryn Halverson, Assistant Professor in the Department of Nursing at Brock University, issues a call to action and a plea for help, urging us to listen to what new nurses are saying.
Suffering from vertigo or dizziness problem

The future of AVS, dizziness, and vertigo in emergency departments Part IV: Priorities for...

In the fourth article of this five-part series, Dr Millie Nakatsuka discusses how reform must be integrated into the broader context of the public health landscape.
Schooling fish swimming together in crystal clear ocean

Fish hearts expose toxic truth about our cardiovascular health

Professor Holly Shiels, from the University of Manchester, is the Director of the Company of Biologists and the President of the Fisheries Society of the British Isles. She charts a toxic tide by tracing the path of pollutants from fish hearts to human cardiovascular health.
Hands Of Woman Deformed From Rheumatoid Arthritis. PainRheumatoid arthritis hands. MacroRheumatoid arthritis hands. Macro

Stem cell therapy for osteoarthritis: Functional cartilage regeneration using 3d bioprinting technology

Osteoarthritis presents a significant societal and economic burden. Stina Simonsson from the University of Gothenburg explains how EU-funded projects are using 3D bioprinting to create functional cartilage for OA treatment.
Figure 1. Personalized medicine in RESCUER. From bottom left. Clinical and molecular data are collected from clinical trials from Norway, Germany and Spain and processed to identify signatures/ molecular barcodes of resistance to hormonal-, immune-, and chemotherapy, respectively. Pathological images are subjected to digital cartography and together with the molecular barcodes used for patient stratification towards improved treatment strategies. The generated data is used to parameterize mathematical models of prediction of treatment outcome.

Breast cancer prevention: Precision medicine and health

Biobank Norway Project experts chart the journey from precision medicine to precision health when it comes to breast cancer prevention.
Closeup young woman sitting on sofa and feeling knee pain and she massage her knee at home. Healthcare and medical concept.

Mobilizing pain care knowledge in Canada

Norm Buckley and Jason Busse from the Michael G. DeGroote Institute for Pain Research & Care discuss the mobilization of knowledge about the pain environment in Canada, focusing on the role of an ad hoc community-based organization.
Creative image of embryonic stem cells, cellular therapy, 3d illustration

Protecting cancer survivors across Europe from financial discrimination: The right to be forgotten

Mark Lawler and Françoise Meunier highlight the financial discrimination that many cancer survivors face despite being cured of their disease and propose a data-informed legal solution so that cancer patients are not punished for a previous cancer diagnosis.
Illustration of prisoner looking the light coming from outside the bars, abstract redemption concept

Advancing knowledge about criminal justice and mental health

Researchers with expertise in criminal law, philosophy, psychiatry and psychology are combining their knowledge to explore how mental disorders are approached within criminal law and contribute to better legal and forensic practices.
Sepsis Canada

Making preclinical sepsis research stronger, faster, and more responsive to patients

Sepsis represents a significant global burden. The National Preclinical Sepsis Platform (NPSP) is leading vital sepsis research, informing policy, driving innovation, and ultimately saving lives.
Multiracial senior women having fun together after sport workout outdoor - Main focus on african female face

Seasonality and climate change: Challenges for physical activity in older adults

Research indicates seasonal variations in physical activity levels among adults in different climates due to temperature and humidity. Climate change’s increasing extreme weather may significantly affect physical activity in older adults already struggling to meet activity guidelines. Isabelle J. Dionne from the Université de Sherbrooke explains.
Image: © SolarCloud | iStock

Hormonal contraceptives and women’s mental health – A long-term perspective

Belinda Pletzer of the University of Salzburg discusses the importance of researching the mental health effects of hormonal contraceptives and the need to identify women at risk for adverse mood reactions before they start hormonal contraception.

Engineering interkingdom communication for next-generation therapeutic approaches

Brian Snyder and Christopher H. Contag, from Michigan State University, discuss engineering interkingdom communication, which is not for palace intrigue, but for next-generation therapeutic approaches they argue.

Adipose tissue: A treasure trove of stem cells for regenerative medicine

Adipose tissue, commonly known as fat, has long been considered a mere energy reservoir. However, recent discoveries have revolutionized our understanding of this tissue, placing it at the heart of advances in stem cells and regenerative medicine.
Photography of incense stick smoke.

Modeling cigarette smoking exposure in subsets of the population

Understanding and acknowledging various factors that impact cigarette smoking and exposure is critical when creating public health interventions to curb tobacco use. Here, Theodore R. Holford from Yale University discusses the impact of different approaches to tobacco control.
A female patient is refusing to take a shot from her doctor. She is holding her hands in front of her doctor as if defending herself from the syringe and the needle.

Vaccine hesitancy and the challenge of successful scientific communication

Drawing on personal experiences and public discourse, Dr. Klaus Eyer, an Associate Professor at Aarhus University, explores the challenges of communicating about vaccine science to address vaccine hesitancy.
Large Group of diverse people profile view hand drawn, with different emotional / mental states and thoughts.

Understanding and predicting the intergenerational transmission of mental illness

The FAMILY consortium aims to improve the lives of mentally ill persons and their families by focusing on understanding the mechanisms of intergenerational transmission of mental illness from parent to child.
Figure 1: Three different non-genetically encoded scaffolds regulate cellular responses. The interactions between them are normally kept in check to ensure that cells remain healthy and functional, with arrows indicating positive interactions and dotted lines with a bar at one end representing inhibitory events. The Z-RNAs expressed from the genome will cause inflammatory cell death when interferon induces high levels of ZBP1 (as indicated by the scarlet shading). That response eliminates virally infected cells, other aged cells that no longer function normally, and those inflamed cells that support the growth of malignancies.

Cellular scaffolding: Crowdsourcing cellular responses in health and disease

In this article, Dr Alan Herbert discusses how different types of cellular scaffolds interact and impact the risk of diseases, citing the example of Z-RNAs pushing cells to inflammatory states in tumors and autoimmune conditions, setting the stage for new therapeutics.

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