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Figure 1: Risk and protective factors according to Substance Abuse and Mental Health Services Administration (2021)

Risk factors for cannabis use in young people

With cannabis use among young people on the rise, Ronan Fleury, Prof Bobby Smyth and Prof Mary Cannon. discuss the mental and physical impacts and the importance of understanding the risk factors.
Cancer malignant cells - 3d rendered image, abstract enhanced scanning electron micrograph (SEM) of cancer malignant cells. Visual of overall shape of the cell's surface at a very high magnification. Medical research concept.

From selfish silo to collaborative culture – embracing data-enabled cancer research

Aedin Culhane and Mark Lawler, Co-Leads of the eHealth Hub for Cancer, reflect on their data-enabled cancer research journeys, how their collaborative team science approach has reaped significant dividends in cancer research and policy and how the hub is inducing a paradigm shift in how health data are deployed on the island of Ireland.
Microscopic preparation, tissue plant

What imaging reveals about engineered endosymbionts

Ashley V. Makela and Christopher H. Contag from the Institute for Quantitative Health Science and Engineering, walk us through watching living therapeutics in action, including what imaging reveals about engineered endosymbionts.
Figure 1. Rats with prolonged lactation are protected against high-fat diet-induced obesity.

Prolonged lactation: Preventing obesity since infancy

Dr Vincent Prevot and Professors Markus Schwaninger and Ruben Nogueiras explain the significance of the perinatal maternal lifestyle, specifically prolonged lactation, in shielding offspring from chronic disease.
Figure 1: Beneficial effects of Kinase inhibition for multiple indications

Protein kinases for combating inflammatory disease

Julie Blaising, Discovery Project Leader in Immunology at F. Hoffmann-La Roche Ltd, tells us why protein kinases are an effective target for treating many chronic inflammatory disorders.

AI-empowered neural processing for intelligent human-machine interface and biomedical devices

Jie Gu, Associate Professor from Northwestern University, examines AI-empowered neural processing for intelligent human-machine interface and biomedical devices.
Neurons. Concept. 3D Render

Symptomatic vs. Disease-modifying treatments in neurological diseases: Where next?

An optimal drug for chronic neurological disease would slow down disease progression in the long term, with short-term symptomatic benefits. This would shorten clinical development timelines and reduce the cost and risk level for drug developers. Henri Huttunen Chief Scientific Officer (CSO) at Herantis Pharma Plc explains.
Image: © Alena Butusava | iStock

BRAV3 Project: Cardiac regenerative medicine

Prof Felipe Prósper, Head of Department, and Dr Manuel Mazo, from the University of Navarra & Clínica Universidad de Navarra, shares his expertise in cardiovascular diseases, focusing on the work of the BRAV3 project, which includes research in cardiac regenerative medicine.
abs Lactobacillus Bulgaricus Bacteria - 3d rendered microbiology image. Medical research, health-care concept.

National sepsis strategy to improve knowledge, prevention and treatment

Discover what you need to know about sepsis from a top group of experts, including their call for a national sepsis strategy to improve its knowledge, prevention, and treatment to save lives.
Unhappy person having a headache after physical injury at home

Treatment of migraines: Minimally invasive surgery, regenerative approach and botox

Giorgio Pietramaggiori and Saja Scherer, MD, from the Global Medical Institute, describe a revolution in the treatment of migraines: minimally invasive surgery, a regenerative approach and Botox.
Cancer cells vis - 3d rendered image, enhanced scanning electron micrograph (SEM) of cancer cell. Visual of overall shape of the cell's surface at a very high magnification. Medical research concept.

Personalized cancer medicines

Dr. Priya Hays, PhD, CEO and Science Writer at Hays Documentation Specialists, LLC, guides us through the world of personalized cancer medicines.
Close up the rat in dry leaf background. Animal contagious disease concept.

Getting leptospirosis onto the lists of neglected tropical diseases

Leptospirosis is a globally important infectious disease, but neglected to the extent that it’s not on WHO’s or FDA’s neglected tropical diseases lists; this needs to change.
retired specialists, Hospital Medical Doctor Office: Portrait of Professional Female Physician Working on Desktop Computer, Talking to a Patient on a Internet Video Call Consultations, Writing Digital Prescriptions

Recruiting retired specialists back into part-time practice via telemedicine

Richard J. Santen, MD, Emeritus Professor of Medicine at the University of Virginia in Charlottesville, Virginia, U.S., looks at how to recruit retired specialists to practice part-time via telemedicine.
Blue & Green Medicine Tables.

How the “tides” have turned in pharma manufacturing

Two seasoned experts from CPI, Medicines Manufacturing Innovation Centre, detail how the “tides” have turned in pharma manufacturing.
Robotic screening platform for T cell growth Photo: SINTEF/Geir Mogen

T cells successfully fighting cancer

Else Marit Inderberg and Sébastien Wälchli from Oslo University Hospital explore what we need to know about T cells successfully fighting cancer.
Table 1. Demographics of Libby, MT study participants (n=296., with percentage of the population given in parentheses.

Asbestos-induced autoantibodies across Libby demographics

Aiden Niblett, Jean Pfau, and Kinta Serve focus on asbestos-induced autoantibodies across different demographics in Libby. They emphasize the importance of understanding the impact of asbestos.
Vaccine Coronavirus COVID-19 on Conveyor Belt

Learning from the COVID-19 Pandemic: Next-generation universal vaccines and immunotherapeutic research

With the COVID-19 pandemic behind us, we need to focus on universal vaccines and/or immunotherapeutic strategies and technologies to tackle ongoing endemic infections with SARS-CoV2, influenza, and RSV and prepare for any future pandemics, says Dr Babita Agrawal.
Photography of steam.

Cigarette smoking focus: A modeling approach for estimating the impact of health programs

Theodore R. Holford from Yale University charts a modeling approach for estimating the impact of health programs in this cigarette smoking research focus.
Still image of highly dynamic chromatin (red) interacts with Arc pucta (green). Shown is a small detail of a neuronal nucleus imaged by high-resolution microscopy. Notice how finger-like extensions of the chromatin transiently visit Arc pucta. The movie is sped up 10 times.

Arc: A new target for treating alzheimer’s disease

Antonius M. VanDongen, Associate Professor from Duke University, walks us through Arc, a new target for treating Alzheimer’s disease.
Abstract fractal art background which could suggest a neural network, or the nervous system, or other themes of connectivity and biology, neuropathic pain

Treating neuropathic pain and nicotine dependence: Epibatidine derivatives as potential therapeutics

Lance R. McMahon, Ph.D. and Jenny L. Wilkerson, Ph.D. from Texas Tech University Health Sciences Center, describe the search for the magic bullet to treat both neuropathic pain and nicotine dependence using novel epibatidine derivatives as potential therapeutics.

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