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E. coli genomes, big data, and messy biology

Here, David Ussery from the Department of BioMedical Informatics, UAMS, details E. coli genome diversity, big data, and messy biology. New methods, we discover, allow for the comparison of millions of bacterial genomes in a few days and the confident assignment of taxonomic clusters.
Graphic representation of outcomes derived from the application of microbes.

SUS-MIRRI.IT: How microbial culture collections hold up a more sustainable, competitive, and resilient bioeconomy

Marino Moretti and Giovanna Cristina Varese, Project Manager and Scientific Coordinator, respectively, of the EU-funded project SUS-MIRRI.IT, on behalf of all project partners, explain how safeguarding microbial biodiversity is extremely paramount for the future of our planet.
Figure 1. Visualization of direct and mediated extracellular electron transfer by bacteria.

Microbial extracellular electron transfer in the human gastrointestinal tract

Gratian Ting and Arpita Bose from Washington University in St. Louis discuss the fascinating role that extracellular electron transfer plays within the human gut.
Petri dish with close up colourful detailed bubbles on a white background. Marco shot with a white backlight. mechanical energy

Mechanical energy at the origins of life

Did mechanical energy power life’s origins before chemical energy such as ATP was available?
Snowy owl flying on a sunny day. Spread wings. Quebec's official bird.

Modelling biodiversity is an essential part of its protection

Professor Guillaume Blanchet from Université de Sherbrooke considers why modelling biodiversity is an essential part of protection and how we can model biodiversity better.
Team of Medical Research Scientists Conduct Experiments with Help of Microscope, Test Tubes, Micropipette and Desktop Computer. Modern Biological Applied Science Laboratory with Diverse Colleagues.

Exposomics: A shift in biomedical research with potential to improve human health

Recent advances in exposomics offer an exciting opportunity to comprehensively catalog human exposures and link them to biological responses determining health and disease. Pamela J. Lein, Ph.D. from the University of California, tells us more.
Figure 1: Three different non-genetically encoded scaffolds regulate cellular responses. The interactions between them are normally kept in check to ensure that cells remain healthy and functional, with arrows indicating positive interactions and dotted lines with a bar at one end representing inhibitory events. The Z-RNAs expressed from the genome will cause inflammatory cell death when interferon induces high levels of ZBP1 (as indicated by the scarlet shading). That response eliminates virally infected cells, other aged cells that no longer function normally, and those inflamed cells that support the growth of malignancies.

Cellular scaffolding: Crowdsourcing cellular responses in health and disease

In this article, Dr Alan Herbert discusses how different types of cellular scaffolds interact and impact the risk of diseases, citing the example of Z-RNAs pushing cells to inflammatory states in tumors and autoimmune conditions, setting the stage for new therapeutics.
Scientist, microscope and analysis in lab for healthcare, innovation and development in stem cell research. Black woman, investigation and experiment with biotech for dna, exam or test for bacteria

The vital role of sustainable chemistry

Prof. Dr. Cecilia Van Cauwenberghe, PhD, MSc, BS, MBA, Research Director at Everest Group, sheds light on sustainable chemistry, including how breakthrough innovations drive global change.

A century of NAD+ insights drives aging science and solutions innovations

Dr. Rebecca Crews from Renue By Science, LLC, outlines a century of NAD+ insights driving aging science and, innovative solutions and much more.
Neuron cells system - 3d rendered image of Neuron cell network on black background. Hologram view interconnected neurons cells with electrical pulses. Conceptual medical image. Glowing synapse. Healthcare concept.

Timely diagnosis and intervention for people with dementia

Jockey Club Centre for Positive Ageing experts highlight the importance of timely diagnosis and intervention for people with dementia.
Stack of asbestos roofing sheets. Carcinogenic eternite.

Asbestos disease pathogenesis: The long and short of it

Jean Pfau and Kinta Serve explore a critical and novel hypothesis concerning the size of fibers in asbestos disease pathogenesis.
vaccinations in Africa, vaccines, vaccines and biologics

Catalysing vaccines and biologics manufacturing in Africa

Professor Faith Osier, Director of the Chanjo Hub at Imperial College London, shares her vision for vaccines and biologics manufacturing in Africa to secure lives and livelihoods and drive economic growth.

Harnessing hybrid molecules for drug development

Stoyanka Nikolova, Professor from Paisii Hilendarski Plovdiv University, discusses the potential of harnessing hybrid molecules for drug development and their possible application in addressing the clinical challenge of irritable bowel syndrome.
1-day RGB composite image of the Mediterranean Sea as observed by Sentinel 3A and 3B on July 14th, 2022. ©EUMETSAT [2024] phytoplankton

PETRI-MED: Enhancing marine phytoplankton diversity monitoring in the Mediterranean

Preserving biodiversity is crucial for sustaining life on Earth. Unfortunately, it is facing growing threats. Marco Talone and the PETRI-MED Team discuss their objectives for the PETRI-MED project and explain why it is urgently necessary.
3D Abstract Red Blue Background Vortex Technological Concept, Fiber Optic Particles (Depth of field) - Polylactic Acid

Floreon technology, redefining polylactic acid

Dr Andrew Gill, CTO, and Dr Sandrine Garnier, CEO of Floreon Technology Ltd., explain how the company is redefining Polylactic Acid, starting with who they are and what they offer.

Protecting the human epigenome with nutritional epigenetics intervention programs

Dr Renee J. Dufault, Executive Director at the Food Ingredient and Health Research Institute, explains the significance of nutritional epigenetics in understanding the impact of nutrients and dietary chemicals on gene expression patterns, as well as their role in the development of conditions such as autism and ADHD.

Flipons: The discovery of Z-DNA and soft-wired genomes

Alan Herbert, Founder and President of InsideOutBio, discusses alternative DNA conformations and understanding of their biological functions.
Blue electromagnetic field, computer generated abstract background

Extracellular electron transfer explained

Arpita Bose, PhD from Washington University in St. Louis, guides us through host-associated impacts and biotechnological applications of extracellular electron transfer in electrochemically active bacteria.
Figure 1: Microbes particulate the cycles of four important elements.

Microbes as high-potential green resource producers

Hui-Ping Chuang, Assistant researcher at the Sustainable Environment Research Laboratories of the National Cheng Kung University, shares insights into the vital role of microbes in waste removal and sustainable resource generation.
Green Light Bulb

Fluorescent sensors for detecting anions

Nicola Edwards, Associate Professor of Chemistry at the University of St. Joseph, is conducting research on the development of fluorescent sensors for anion detection.

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