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Antibody binding to human cell receptors is a crucial aspect of the immune response and plays a fundamental role in various physiological processes, including immune defense, signaling, and regulation of cellular functions. Antibodies, also known as immunoglobulins, are proteins produced by the immune system in response to the presence of foreign substances, such as pathogens or abnormal cells.

High-resolution snapshots of antibody repertoires as potential correlates of protection

Klaus Eyer from ETH Zurich describes high-resolution snapshots of antibody repertoires as potential correlates of protection.

Microfluidic microbial bioreactors: How studying microbes at the microscale can help empower microbiology

Long before the existence of microbes was known, humans were unknowingly harnessing their power through practices such as brewing, bread leavening, or cheesemaking. These processes extended the shelf life of food, enhanced its nutritional value, and significantly contributed to the advancement of industry and civilization.
Figure 1. Elements of the operational RNA code in the tRNA acceptor stem. A. Bases in the tRNA acceptor stem encode two aspects of amino acid physical chemistry—size and polarity—that determine protein folding. B. Acceptor stem bases preceded the anticodon stem-loop and code other properties. C. The oldest parts of Class I and II AARS could already discriminate between both amino acid and RNA substrates (6) .

tRNA: The operational RNA code and protein folding

Charles W. Carter, Jr., from the Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, relates molecular recognition used in genetic coding to structures of aminoacyl-tRNA synthetases and their cognate tRNAs.

Digital Life Norway (DLN) Initiative to foster and boost transdisciplinary biotechnology research and innovation

Meeting the rapid developments in biotechnology by fostering transdisciplinarity, including digitalisation and big data, to create convergence for innovation in a virtual centre.

Removing carbon dioxide from the atmosphere

The agricultural sector plays a decisive role in tackling climate change. GERICS explores what actors of the agricultural sector think of removing carbon dioxide and what support they need from science.
Figure 2. A pair of personalized 3D-printed shoe soles. Source: AITIIP

Bio-based solutions for a circular economy

Principal Scientist Ulla Forsström from the VTT Technical Research Centre of Finland Ltd tells us about the INN-PRESSME Open Innovation Test Bed project, which aims to develop novel, sustainable and recyclable bio-based solutions to replace fossil-based plastic.
Group of bacteria such as Escherichia coli, Helicobacter pylori or salmonella 3D rendering illustration on blue background. Microbiology, medical, bacteriology, biology, science, healthcare, medicine, infection concepts.

Microbe development for the biomanufacturing age

Joe Price, Dr Kang Lan Tee & Prof Tuck Seng Wong, explore adopting a holistic approach to microbe development for the age of biomanufacturing.
circular economy, economy, linear economy, economy

Purple non-sulfur bacteria and the circular economy

Arpita Bose, Associate Professor at Washington University in St. Louis, discusses the potential of microbial solutions in supporting sustainable and environmentally responsible alternatives to the traditional linear economy.
A scientist using a pipette with a microtiter plate and a petri dish

AI and modern experimental biology: A historical perspective

Ute Deichmann, Director of the Jacques Loeb Centre for the History and Philosophy of the Life Sciences at Ben-Gurion University of the Negev, discusses the adoption and limitations of Artificial Intelligence within modern experimental biology.
Fig 1: The Abernathy-Utterback curve represents the innovation pipeline in this case as it transitions through the production of two consecutive stable products. It has three phases: 1) the Fluid Phase, where flexibility is needed because of uncertainty in the product idea, the technology and the market and in this case, the needs of the research community; 2) the Transitional Phase, when the technology, the application and the customer’s needs are better understood until a ‘dominant design’ emerges; 3,) the Specific Phase the ‘dominant design’ shifts from being different to having good performance

FFEA software: Repeated early innovation

Dr Joanna Leng, Senior Research Software Engineering Fellow at the University of Leeds, discusses software with repeated early innovation using the example of the FFEA software.
blue water mirror. abstract background of rippled water surface

Harnessing redox power for biotechnological application in purple non-sulphur bacteria

Here we explore purple non-sulfur bacteria (PNSB) and some of its biotech applications, with a focus on how these applications have been enhanced by manipulating the flow of reducing power.
Cancer Cells under microscope background 3D illustration

Bio-inspired design approaches to artificial blood technology: Oxygen carriers

Allan Doctor, MD, Professor of Pediatrics at the University of Maryland School of Medicine, shares his expertise on bio-inspired design approaches to artificial blood technology: oxygen carriers.
Figure 1: Scientific innovations in ECS research and drug discovery that will strongly impact the future discovery of improved and tailor-made CB2R medicines.

CB₂R ligands to treat inflammatory diseases

Researchers discuss how scientific innovations might influence the discovery of future tailor-made CB2R-based anti-inflammatory treatments.

Interdisciplinary research on the splitting process of various particles

Professor Ken Naitoh from the Department of Applied Mechanics and Aerospace Engineering at Waseda University in Japan, walks us through universal laws discovered from outstanding integrated interdisciplinary research on the splitting processes of various particles.
Soap bubbles on a pink background,Texture background.

Artificial intelligence (AI) and biomaterials: A perfect BandAId™

Thomas J Webster, Ph.D., Professor and Entrepreneur, is investigating the potential of AI in medical applications and biomaterial production.

Computational biology is poised to advance precision medicine with machine learning

Today, scientists are attempting to model whole cells using computational biology, building virtual cells that capture the dynamics of living.
Skin tissue cells and fat tissue cells ,dermis and adipocytes

Microbiome of the skin: The good and the bad

Chronic wounds are a significant burden to patients and health systems; Manuela Martins-Green from the University of California tells us how her research in understanding the dynamics of wound healing could aid new approaches to wound care.
Pills On Yellow Background, symbolising drug repositioning

Can we do drug repositioning without disease gene expression?

Chuo University’s Professor Y-h. Taguchi examines the application of cutting-edge single-cell-based measurements in drug repositioning.
abstract background with space for text, algal infection

Early detection of algal infection using direct real-time chemical ionization mass spectrometry

Robert S. Pomeroy, Teaching Professor at UC San Diego, guides us through the early detection of algal infections using direct real-time chemical ionization mass spectrometry.
AMR,

Bacteriophages: Nature’s remedy for tackling superbugs and antimicrobial resistance

Given the increasing threat of antimicrobial resistance, Gunther Vanwezer, CEO of Vésale Bioscience, explains how bacteriophages offer a promising natural solution and outlines the company’s efforts to become a pioneer in the development of innovative, personalised and sustainable phage-based therapy solutions.

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