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Empowering voices: Breaking mental health stigma

John Hoey and Mary Cannon from Department of Psychiatry, RCSI University of Medicine and Health Sciences, Dublin, Ireland, share their research around breaking mental health stigma to empower voices.
Suffering from vertigo or dizziness problem

The future of AVS, dizziness, and vertigo in emergency departments Part IV: Priorities for...

In the fourth article of this five-part series, Dr Millie Nakatsuka discusses how reform must be integrated into the broader context of the public health landscape.

The sociology of bridge: Sport recognition for mind sports

The game of contract bridge, as we know it today, originated in the 20th century – but what lies ahead for bridge as a mind sport? Professor Samantha Punch, the academic behind “Bridge: A MindSport For All”, provides the answer.
Brain activity,Human brain damage,Neural network,Artificial intelligence and idea concept

A novel avenue to explore in the treatment of dementia

A collaborative project between the University of South Florida and The Healthy Aging Company is exploring how a new biological entity called ALF5755 could be a candidate drug for the treatment of dementia and Alzheimer’s disease.
Figure 1: Electrocochleography-total response (ECochG-TR) measured at the round window prior to cochlear implant insertion (RW-ECochG-TR) shows a weak correlation with performance in noise (AzBio +10 dB signal-to-noise ratio). Similarly, the MoCA score, a measure of cognitive function, also exhibits a weak correlation with performance in noise. However, a multivariate model incorporating both cochlear health (ECochG-TR), cognition (MoCA score), and their interaction (product of ECochG-TR and MoCA) explains 46.0% of the variability in noise performance. This finding suggests that while good cochlear health is necessary for strong performance in noise, it is not sufficient on its own – it must be complemented by adequate cognitive function.

Cognitive function and electrode mapping’s role in cochlear implant performance

Amit Walia, Matthew Shew and Craig A. Buchman from Washington University School of Medicine, detail the role of cognitive function and electrode mapping in cochlear implant performance.

A game that poses a challenge to artificial intelligence

Steven J. Brams, hailing from New York University, unveils a game that poses a challenge to artificial intelligence.
Abstract background from nature using motion, radial or zoom blur - metphor for vertigo, deep space, dizzy, unstable mental health illness, constrained, spinning wheel

The future of AVS, dizziness, and vertigo in emergency departments Part iii: A tyranny...

In the third article of this five-part series, Dr Millie Nakatsuka discusses the impact of isolation on health equity and the medical decision-making for emergency presentations of acute vestibular syndrome (AVS)
Table 1: Change in neuropsychological performance on the flame composite and the individual factors over two years in people with amnestic MCI (n = 548) (3)

Innovation in clinical trials in brain health: Computerised assessment and remote clinical trials

New clinical trials in brain health require innovative methodologies for targeted recruitment and longitudinal assessment. Professor Anne Corbett outlines how her team’s PROTECT portfolio can overcome challenges in trials of cognitive health interventions, offering solutions for intelligent trial design.
Cellular therapy. 3d illustration

The ethical and legal challenges of cell donation for brain organoid research

Ethical and legal concerns raised by the use of human biological materials, especially cells from adult donors and foetal tissues, must be thoroughly examined.
CorTec Brain Interchange Implant for Stroke Treatment

Stroke rehabilitation milestone, neurological conditions and future therapy

Martin Schuettler, Chief Technology Officer of CorTec GmbH, walks us through a groundbreaking achievement in the development of future therapies for neurological conditions like stroke.
Unhappy person having a headache after physical injury at home

Treatment of migraines: Minimally invasive surgery, regenerative approach and botox

Giorgio Pietramaggiori and Saja Scherer, MD, from the Global Medical Institute, describe a revolution in the treatment of migraines: minimally invasive surgery, a regenerative approach and Botox.
Abstract curly tendrils background.

Invasive electrical stimulation for stroke treatment

The CorTec Brain Interchange system is a potential tool to improve motor rehabilitation after stroke (Schuettler, 2023). Here, it is sketched how results from studies of other groups are combined to form CorTec’s vision of a new therapy and how first human data was collected to prove the systems therapy capability.
Digitally generated image, perfectly usable for all kinds of topics related to digital innovations, AI, data processing, network security or technology and computer science in general.

Flame system: Computerised cognitive assessment for remote brain health monitoring

Monitoring brain health, particularly cognition, in older adults is increasingly recognised as a significant priority for research, healthcare and broader public health. Find out here about the development and validation of the FLAME System, a computerised cognitive assessment for remote brain health monitoring.
Image: © peterschreiber.media | iStock

A guide for occipital neuralgia patients

Giorgio Pietramaggiori, MD, PhD and Saja Scherer, MD, from the Global Medical Institute, help us to understand occipital neuralgia in this detailed patient guide.
Figure 1: The central nervous system (CNS) is protected from mechanical injury by the skull (A) and from chemical noxious agents by the blood-brain barrier (B, C). The latter consists of the endothelial barrier in most parts of the CNS (B) and the tanycytic barrier in the hypothalamus (C). We develop gene vectors transducing endothelial cells and tanycytes to treat genetic and non-genetic diseases of the brain.

Bridging brain barriers for gene therapy

Reflecting on the challenges in treating brain diseases, this article explores ways to transduce the blood-brain barrier as well as the critical role of tanycytes as a target for gene therapy vectors.

AI healthcare research: Pioneering iSMART Lab

Dr Narges Armanfard, Professor, talks us through the AI healthcare research at McGill University which is spearheading a groundbreaking initiative – the iSMART Lab.
High Energy Consuming Processes in Neurons: Axonal transport Synaptic vesicle recycling, Neurotransmitter release/reuptake, ion pumping, organelle maintenance, protein turnover. therapeutics for neurodegenerative disease

Contribution of oxidative stress to neurodegenerative disease

Paul A. Hyslop, from Arkley BioTek Indianapolis, details an ongoing specific research approach to identify, characterize, and validate physiologically relevant neuronal targets of H2O2 in designing therapeutics for neurodegenerative disease progression.
close up shots of fire fighting equipment

Internet-delivered cognitive behavioural therapy

Heather D. Hadjistavropoulos, Hugh C. McCall, and Jill A. B. Price, walk us through internet-delivered cognitive behavioral therapy tailored to public safety personnel.
colourful brain - dementia prevention

Dementia prevention: Raising awareness about dementia and risk reduction

We hear from Dr Anthony J. Levinson, who is part of an academic group developing evidence-based online resources to complement dementia prevention strategies and support care partners.
1: Electrode Model Module 2: Electrode Connector 3: Implant Module 4: Headpiece (Wireless Power Supply of Implant Module) 5: Communication Unit (Wireless Communication with Implant Module) A: Trigger Input B: PC Cable Connector C: Headpiece Cable Connector 6: Personal Computer (PC)

Preparing for a clinical study on implant-enhance stroke rehabilitation

Martin Schuettler, Chief Technology Officer at CorTec GmbH, addresses key questions around the development of the company’s innovative Brain Interchange System to support stroke rehabilitation therapy.

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