Home 2024

Archives

Figure. G-quadruplexes cycle between a four-stranded fold and the Watson and Crick B-DNA conformation. Nature uses many different tissue-specific proteins to drive the cycle. Therapeutic approaches to targeting G-quadruplexes include drugs, such as PROTACS that send them to garbage, small molecules that either promote or disrupt their formation, or small RNAs that target the DNA or RNAs sequences that form them.

Targeting the most complex flipon of them all in the fight against cancers

In this article, Alan Herbert, the Founder, and President of InsideOutBio, guides us through targeting the most complex flipon of them all in the fight against cancers.
Cancer in the blood outbreak and treatment for malignant cells in a human body caused by carcinogens and genetics with a cancerous cell as an immunotherapy and leukemia or lymphoma symbol and medical therapy as a 3D render.

A novel approach to cancer chemotherapy

Richard F. Ludueña, Professor Emeritus at the University of Texas Health San Antonio, discusses his innovative approach to cancer chemotherapy, which could significantly enhance its effectiveness.

Fuelling the global supply of medical radioisotopes for cancer care

European research reactors play a crucial role in producing medical radioisotopes using nuclear fuel and are transitioning to Low Enriched Uranium (LEU) to meet non-proliferation commitments and global demand. Jared Wight tells us how he and his colleagues are working to ensure a smooth conversion to LEU fuels.
Figure 1. Personalized medicine in RESCUER. From bottom left. Clinical and molecular data are collected from clinical trials from Norway, Germany and Spain and processed to identify signatures/ molecular barcodes of resistance to hormonal-, immune-, and chemotherapy, respectively. Pathological images are subjected to digital cartography and together with the molecular barcodes used for patient stratification towards improved treatment strategies. The generated data is used to parameterize mathematical models of prediction of treatment outcome.

Breast cancer prevention: Precision medicine and health

Biobank Norway Project experts chart the journey from precision medicine to precision health when it comes to breast cancer prevention.
Creative image of embryonic stem cells, cellular therapy, 3d illustration

Protecting cancer survivors across Europe from financial discrimination: The right to be forgotten

Mark Lawler and Françoise Meunier highlight the financial discrimination that many cancer survivors face despite being cured of their disease and propose a data-informed legal solution so that cancer patients are not punished for a previous cancer diagnosis.
Professional female doctor examines results of mammography screening procedure using computer. Mammogram scans of breast tissues displayed on PC screen. Breast cancer prevention. Hospital or clinic.

Artificial intelligence (AI) in mammographic screening in Norway

BreastScreen Norway discusses how the results from their screening programme for early breast cancer detection can influence future artificial intelligence to streamline early breast cancer detection.
Cancer malignant cells - 3d rendered image, abstract enhanced scanning electron micrograph (SEM) of cancer malignant cells. Visual of overall shape of the cell's surface at a very high magnification. Medical research concept.

From selfish silo to collaborative culture – embracing data-enabled cancer research

Aedin Culhane and Mark Lawler, Co-Leads of the eHealth Hub for Cancer, reflect on their data-enabled cancer research journeys, how their collaborative team science approach has reaped significant dividends in cancer research and policy and how the hub is inducing a paradigm shift in how health data are deployed on the island of Ireland.
Cancer cells vis - 3d rendered image, enhanced scanning electron micrograph (SEM) of cancer cell. Visual of overall shape of the cell's surface at a very high magnification. Medical research concept.

Personalized cancer medicines

Dr. Priya Hays, PhD, CEO and Science Writer at Hays Documentation Specialists, LLC, guides us through the world of personalized cancer medicines.
Robotic screening platform for T cell growth Photo: SINTEF/Geir Mogen

T cells successfully fighting cancer

Else Marit Inderberg and Sébastien Wälchli from Oslo University Hospital explore what we need to know about T cells successfully fighting cancer.
Depiction of a blood clot forming inside a blood vessel. 3D illustration, patients with haematological cancers

Assessing blood clot risk in venous catheter selection for patients with haematological cancers

Venous catheters enable patients with haematological cancers to receive vital chemotherapy. However, there is a risk of thrombosis. Consultant Haematologist Priya Sriskandarajah analysed a group of patients with haematological cancers to study the implications of catheter selection.
Detailed photography of constructional material with asbestos fibres. Health harmful and hazards effects. Prolonged inhalation of microscopical fibers causes fatal illnesses including lung cancer, mesothelioma

The risk of malignant pleural mesothelioma

Although the use of asbestos-containing building materials was banned in the UK in 1999, this carcinogenic mineral continues to be a serious health threat. Daniel J. Murphy from the University of Glasgow tells us more.
Curious rodent (mouse/gerbil),, standing on back feet and looking at the camera

Investigating lung cancer using genetically engineered mouse models (GEMMS)

Daniel J. Murphy, Professor of Lung Cancer & Mesothelioma at the University of Glasgow, School of Cancer Sciences, discusses opportunities for improving cancer research and care through the use of genetically engineered mouse models.
Carcinoid tumors are a type of slow-growing cancer that can arise in several places throughout your body. Carcinoid tumors, which are one subset of tumors called neuroendocrine tumors, usually begin in the digestive tract (stomach, appendix, small intestine, colon, rectum) or in the lungs. Site: Ovary

Are nanotextures enough to kill cancer cells?

Nanotextures on nanoparticles and implants to kill cancer cells in a more targeted manner may just be the key to tackling resistance to traditional cancer drugs.

Photodynamic therapy and immune response in solid tumours

Photodynamic therapy can stimulate a person’s own immune system to better recognise – and fight – cancer tumours, say Mary Potasek, PhD and Karl Beeson, PhD of Simphotek and Theresa M Busch, PhD of the Department of Radiation Oncology, University of Pennsylvania.

The European Revert Project: Assisting clinicians in patient treatment

Starting in January 2020, the European REVERT project is now in its final phase. The project blends predictive medicine and AI to enable clinicians to quickly and adequately treat patients.
DNA strand on blue color background. 3d illustration

From byte to bedside: Ushering in the era of digital oncology to outsmart cancer

Philip Dunne and Mark Lawler from the Patrick G Johnston Centre for Cancer Research talk to us about the emerging field of ‘digital oncology’ and how their approach can truly optimise cancer research and care.
Tissue from sellar lesion, microscopy show multiple wet keratin, basaloid appearing cells, inflammatory cells and giant cells. Diagnosis Craniopharyngioma.

Current and future therapy for BRAF-mutant pediatric glioma

Professor Peter J. Houghton from the Greehey Children’s Cancer Research Institute discusses new approaches to pediatric cancer treatment specifically for BRAF-mutant pediatric glioma.
Close up of woman holding pink ribbon for breast cancer awarness. Detail of female hand holding pink awareness ribbon. Young woman supporting living with women's breast tumor.

RESCUER: Supporting new concepts for breast cancer subtypes treatment

RESCUER is an EU Horizon 2020 project, coordinated by the University of Oslo, Norway, that aims to predict treatment response and test new combinational therapies for complex breast cancer subtypes.
Figure 1: Immunofluorescent image of OVCAR3 cells in culture showing that cells are at different stages of the cell cycle. P53 (green) is nuclear in all cells that are not dividing, including PGCCs that are multinuclear (a) and (b). PGCC during abnormal cytokinesis (c). P53 is redistributed in cells undergoing normal mitosis where the condensed chromosomes are either at the midbody (d) or are undergoing cytokinesis (e). (1)

Controlling ovarian cancer: An introduction to detection and treatment

With current strategies proving inadequate, what needs to be done is to further the research into detecting, treating, and controlling ovarian cancer.
Figure 1: Potential employment of hydrogen therapy for cancer treatment. Hydrogen administration can exert antitumoral effects by different molecular mechanisms, including the regulation of intracellular ROS production, the reduction of acute/chronic inflammation in damaged tissues, the modulation of immune response, and a better selectivity towards cancer cells than normal cells, which associates with a good safety profile of this treatment.

Hydrogen therapy: An emerging therapeutic strategy in cancer treatment?

Professor Giovanni Brandi (1,2) and Dr Simona Tavolari (1,2) from the University of Bologna discuss findings from preclinical and clinical studies that highlight the potential of hydrogen therapy in cancer treatment.

Follow Us

Advertisements