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Probing the individuality of cells and molecules

Sotaro Uemura, Professor at the University of Tokyo, probes the individuality of cells and molecules.

Options for stroke survivors: From stroke to conventional therapy

Discovery of novel treatment options for stroke survivors – requirements for implanted systems.
Brain activity,Human brain damage,Neural network,Artificial intelligence and idea concept

Innovative gene therapy approaches for brain tumour-related epilepsy

Professor Mark Cunningham and Dr Kate Connor from Trinity College Dublin discuss the burden of brain tumour-related epilepsy and why novel therapies are urgently needed to improve the quality of life for those affected.
Lijuan Yuan with Gn pig jpg

Gnotobiotic pig models: Illuminating the enigma of human norovirus infection and immunity

Dr Lijuan Yuan and her team have studied human noroviruses (HuNoV) in gnotobiotic pigs for over 15 years. Here, she explains how such research is advancing our understanding of HuNoV pathogenesis, infectivity, and immunity.
Pills On Yellow Background, symbolising drug repositioning

Can we do drug repositioning without disease gene expression?

Chuo University’s Professor Y-h. Taguchi examines the application of cutting-edge single-cell-based measurements in drug repositioning.
Figure 1: Immunomodulatory therapies are effective during the relapsing-remitting phase of MS, when immune cells are found in active lesions, but fail to ameliorate progressive decline and irreversible clinical disability. Increased axonal injury correlates with lack of immune cell infiltration but sustained activation of resident CNS glial cells in the progressive phase. These pathological findings are consistent with MRI imaging studies demonstrating virtually no new lesions occurring during progressive MS. Additionally, at the time of MS diagnosis there is evidence of prior lesion activity by MRI imaging supporting that the future development of neuroprotective strategies should be administered in combination with immunomodulatory therapies.

Targeting the central nervous system: The future of therapeutic strategies for MS

Tara M. DeSilva from the Department of Neurosciences, Cleveland Clinic, looks at the future of therapeutic strategies for MS, focusing on targeting the central nervous system.
Green forest aerial view. Drone photography. Summer sky. Sustainability. Nature conservation. Morning

Decarbonising the world economy with synthetic biology

Macquarie University Distinguished Professor Ian Paulsen, discusses how synthetic biology can be used to decarbonise the global economy.
Girl Undergoing Eye Examination

Sight loss research: Looking forward to an equitable future

Keith Valentine, Chief Executive of Fight for Sight and Vision Foundation, shares how these newly merged organisations are driving efforts in sight loss research to improve patient care.
Inflammation concept, inflamed human tissues 3d rendering.

CB2R agonists in the clinics: A treasure chest for treating inflammatory diseases

Researchers give an update on clinical trials with CB2R agonists and their potential for the treatment of inflammatory diseases.

Development of a new gene therapy drug as a treatment for hypophosphatasia

The current primary treatment for hypophosphatasia is enzyme replacement therapy; however the development of a new gene therapy drug, ARU-2801, may change the landscape forever.
Sitting on their sofa at home, the senior adult couple smiles and laughs at a joke.

The next frontier in anti-cancer drugs

Dr Anthony J. Berdis, Case Comprehensive Cancer Center discusses the future of cancer treatments and anti-cancer drugs.
Close-up medical syringe with a vaccine, BoNT-A injection

Potential implications of cosmetic BoNT-A use on future treatment options for neuromuscular disorders and...

Given the rise in cosmetic procedures involving BoNT-A, cosmetic physician Dr Mary Dingley discusses the therapeutic implications of antibody-induced resistance on future treatment of various conditions, including post-stroke spacticity and pain disorders.
DNA sequencing gel run science and data genomic genetic analysis background abstract pattern.

AARS urzymes: Experimental biochemistry to map genetic coding

Dr Charlie Carter from the University of North Carolina at Chapel Hill explores how advances in enzymology and phylogenetics enable biochemical measurements that could map the ancestral development of genetic coding.
Petri dish with close up colourful detailed bubbles on a white background. Marco shot with a white backlight.

Drug repositioning without the gene expression of disease cells treated with drugs

Y-h. Taguchi, Professor at the Department of Physics, Chuo University in Japan, provides comments on drug repositioning without the gene expression of disease cells treated with various drugs.
Photomicrograph of Metastatic adenocarcinoma of lung. Pleural fluid FNAC. 200X

Photodynamic Therapy: Killing cancer gently with visible light

Photodynamic therapy, using visible light with lower energy, causes fewer side effects when treating cancer, find Drs. Mary Potasek, Evgueni Parilov, and Karl Beeson, Co-founders of Simphotek, Inc.
Laboratory test tube glassware with dropper biotechnology and medical scientific research

The emergence of precision medicine for oncology

Dr Priya Hays, PhD, considers how the rapid development of precision medicine for oncology has impacted diagnosis, treatment, and clinical outcomes in cancer care.
Carbon nano-tubes are twisted to form a yard (bar: 10um)

Recording and decoding neural signals from the vagus nerve

Dominique M Durand, distinguished Professor of Biomedical Engineering, Case Western Reserve University, Cleveland Ohio, USA, discusses the study of neural signals from the vagus nerve.
Brain activity,Human brain damage,Neural network,Artificial intelligence and idea concept

Progress in development of disease-modifying treatments in Parkinson’s Disease

Henri Huttunen, Chief Scientific Officer, Herantis Pharma Plc, charts progress in the development of disease-modifying treatments for Parkinson’s disease.
image of a gorilla hand showing the function of fingerprints

The function of fingerprints: How can we grip?

Professor Gun-Sik Park, in the Department of Physics and Astronomy at Seoul National University explores the function of fingerprints from a lens of understanding the mechanism of our human ability to grip.
DNA sequencing gel run science and data genomic genetic analysis background abstract pattern.

The link between gene expression and machine learning

Professor Y-h. Taguchi uses tensor decomposition to identify genes associated with altered gene expression caused by drug treatment.

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