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Figure 1: Immunofluorescent image of OVCAR3 cells in culture showing that cells are at different stages of the cell cycle. P53 (green) is nuclear in all cells that are not dividing, including PGCCs that are multinuclear (a) and (b). PGCC during abnormal cytokinesis (c). P53 is redistributed in cells undergoing normal mitosis where the condensed chromosomes are either at the midbody (d) or are undergoing cytokinesis (e). (1)

Controlling ovarian cancer: An introduction to detection and treatment

With current strategies proving inadequate, what needs to be done is to further the research into detecting, treating, and controlling ovarian cancer.
classroom with 3 pre-service teachers sat round

Transforming integrative maker education for STEM: Empowering pre-service teachers

Dr Ginny Chambers and Dr Kamryn York from Point Park University tell us about a project aimed at enhancing integrative maker education through the training of pre-service teachers, focusing on elementary education.
A Hydractinia (type of marine invertebrate) colony rejecting another because they are genetically unrelated

The successes and challenges of organ transplantation

Fadi G. Lakkis, Professor of Surgery at the University of Pittsburgh, charts the successes and challenges of organ transplantation.
Lijuan Yuan with Gn pig jpg

Gnotobiotic pig models: Illuminating the enigma of human norovirus infection and immunity

Dr Lijuan Yuan and her team have studied human noroviruses (HuNoV) in gnotobiotic pigs for over 15 years. Here, she explains how such research is advancing our understanding of HuNoV pathogenesis, infectivity, and immunity.
Meteorological and remote sensing instruments on the West Antarctic Ice Sheet during the AWARE field campaign, sea level rise

West Antarctica’s contribution to sea level rise as Earth’s climate warms

Dr Dan Lubin, Researcher at the Scripps Institution of Oceanography, explores the contribution of West Antarctica to sea level rise as Earth’s climate warms.

Exploring the role of machine learning in materials science and engineering

In this paper, Professor Dane Morgan and Research Scientist Ryan Jacobs, from the University of Wisconsin, Madison, discuss their adventures in the field of machine learning in the areas of materials science and engineering.
Skin tissue cells and fat tissue cells ,dermis and adipocytes

Microbiome of the skin: The good and the bad

Chronic wounds are a significant burden to patients and health systems; Manuela Martins-Green from the University of California tells us how her research in understanding the dynamics of wound healing could aid new approaches to wound care.
Hacker in prison cell. Selective focus. AI generated

The relevance of human flourishing to offender rehabilitation

Sung Joon Jang and Byron R. Johnson, both from Baylor University, turn the spotlight on the relevance of human flourishing to offender rehabilitation in Colombia and South Africa.
abstract background with space for text, algal infection

Early detection of algal infection using direct real-time chemical ionization mass spectrometry

Robert S. Pomeroy, Teaching Professor at UC San Diego, guides us through the early detection of algal infections using direct real-time chemical ionization mass spectrometry.

Decoding the brain’s role in preventing and recovering from knee injuries

Dustin Grooms, Professor of Clinical Neuroscience at Ohio University, tells us about his research on the brain’s role in shaping injury-risk movement patterns and how this knowledge could aid rehabilitation practices and the development of new therapies to mitigate the risk of knee injuries.
medical research in pharmaceutical factory laboratory.

The research experiences for undergraduates (REU) program

Greg M. Swain, hailing from the Department of Chemistry at Michigan State University, examines cross-disciplinary training in sustainable chemistry and chemical processes, including the critical role of mentoring and finding research experiences for undergraduates.
Figure 1: Immunomodulatory therapies are effective during the relapsing-remitting phase of MS, when immune cells are found in active lesions, but fail to ameliorate progressive decline and irreversible clinical disability. Increased axonal injury correlates with lack of immune cell infiltration but sustained activation of resident CNS glial cells in the progressive phase. These pathological findings are consistent with MRI imaging studies demonstrating virtually no new lesions occurring during progressive MS. Additionally, at the time of MS diagnosis there is evidence of prior lesion activity by MRI imaging supporting that the future development of neuroprotective strategies should be administered in combination with immunomodulatory therapies.

Targeting the central nervous system: The future of therapeutic strategies for MS

Tara M. DeSilva from the Department of Neurosciences, Cleveland Clinic, looks at the future of therapeutic strategies for MS, focusing on targeting the central nervous system.
Microscopic photo of a professionally prepared slide demonstrating Plasma cell myeloma from bone marrow aspirate. Wright Giemsa stain.

Developing novel therapies for childhood cancers

Dr Peter J Houghton from Greehey Children’s Cancer Research Institute discusses the obstacles in developing new treatments for childhood cancers and new approaches in preclinical testing.
A beautiful and strong athletic young woman working hard cross fitness workout in low light gym working with medicine ball.

The mechanisms and benefits of exercise

At Wayne State University, Robert Wessells and his team are making significant strides in identifying potential exercise mediators or mimetics that could help mitigate pathologies resulting from prolonged sedentary periods.
A low angle view of a cute adorable 7 week old Chocolate Labrador Retriever puppy eating from a red dog dish that is sitting on a dark hardwood floor with a white baseboard and teal colored wall in the background

Sustainably developing great-tasting pet foods

Samantha Combe and Melissa Vanchina from Hill’s Pet Nutrition discuss the environmental impact of pet food, with a specific focus on sustainable alternatives to food palatants.

Enhancing irrigation effectiveness in vineyards with innovative technologies

Professor Pete W. Jacoby, from Washington State University, walks us through enhancing irrigation effectiveness in vineyards with innovative technologies like automated irrigation.
Scientific analysis of Alzheimer's disease in hospital, conceptual image

Lecanemab and other treatments: Glimmers of hope for alzheimer’s patients

Effective treatments for amyloid-associated neurological diseases are desperately needed; H. Robert Guy, CEO of Amyloid Research Consultants, talks us through the obstacles and opportunities associated with structure-based drug design.

Antimicrobial food packaging: Challenges and achievements

Dr Kay Cooksey, Professor and Cryovac Chair at Clemson University, shares the potential of antimicrobial food packaging in mitigating microbial growth and the obstacles that have hindered the development of commercially available products thus far.
Human brain hologram on black background

Pain regulation and research: Decoding the brain’s response to pain

Professor Patrick Stroman from the Centre for Neuroscience Studies at Queen’s University shares insights into his research on the neural basis of human pain and pain regulation, which is supported by functional magnetic resonance imaging.
Abstract Rainbow Blockchain Pixel Shape Prism Exploding Glitch Futuristic Pattern Funky Offbeat Aspirations Neon Surreal Bandwidth Glowing Flowing Time Machine Nanoparticle Firework Confetti Lens Flare Vitality Zoom Effect Cryptocurrency Mining Stereoscopic Distorted Digitally Generated Image Fractal Fine Art for banner, flyer, card, poster, brochure, presentation 16x9 Format

What is at stake in the psychedelic renaissance?

Professor Erika Dyck, Canada Research Chair in the History of Health & Social Justice, discusses the extensive history and growing medical application of psychedelics known as the psychedelic renaissance.

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