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Cancer Research

From prevention to treatment: The promise of cancer vaccines

Dr Catherine Elliott explores how vaccine advances could transform cancer prevention and treatment, from HPV to an experimental lung cancer vaccine.

Tanning beds triple melanoma risk and cause widespread DNA damage

New research shows tanning bed use nearly triples melanoma risk and causes more extensive DNA mutations than natural sunlight.

Advancing global efforts in cervical cancer elimination

Prebo Barango, Co-chair of the UN Joint Action Group for the Cervical Cancer Elimination Initiative at the World Health Organization (WHO), and Nicholas Banatvala, Head of the Secretariat for the UN Interagency Task Force on the Prevention and Control of Noncommunicable Diseases, discuss the challenges and progress in the efforts to eliminate cervical cancer.

Nuclear waste to cancer cure: UK turns reprocessed uranium into precision medicine

Hundreds of tonnes of reprocessed nuclear material are set to power a new generation of cancer treatments.

Gene therapy achieves world-first remission of “incurable” leukaemia

Scientists at UCL and GOSH have used groundbreaking base-edited CAR‑T cell therapy — BE‑CAR7 — to treat aggressive T‑cell leukaemia, with two‑thirds of patients now disease‑free.

Breakthrough Obe-cel drug for aggressive leukaemia to reach NHS patients

A new immunotherapy for a severe form of blood cancer will soon be available on the NHS, offering new hope to adults whose disease has returned or stopped responding to conventional treatment.

Cancer genomics and global collaboration

The Global Alliance for Genomics and Health (GA4GH) is uniting researchers worldwide to share genomic data responsibly, set open standards, and improve oncology care. Leaders from its Cancer Community discuss the current state of cancer genomics and where the field is headed.

Oxford & GSK launch £50 million experimental medicine programme to prevent cancer

Oxford University and GSK launch a £50 million experimental medicine programme aiming to train the immune system to prevent cancer, paving the way for breakthrough vaccines and early‑stage treatments.

World-first lung cancer prevention vaccine “LungVax” enters phase 1 trial

Cancer Research UK is backing a £2.06 million, first-in-human trial of LungVax, a preventative vaccine designed to prime the immune system against early lung cancer.

EU4Health 2024 launches new wave of projects targeting cancer prevention on early detection

A new set of initiatives, funded under the EU4Health 2024 Work Programme, has begun, continuing to support Europe’s Beating Cancer Plan.

Tiny bladder implant, TAR-200, eliminates cancer in 82% of patients

The TAR‑200 slow‑release bladder implant cleared tumours in 82% of patients with high‑risk non‑muscle‑invasive bladder cancer, offering a promising new treatment approach.

Bioengineered bone marrow model advances leukaemia research

Researchers at the University of Glasgow have developed the first bioengineered human bone-marrow model to test CAR T-cell therapies for ­acute myeloid leukaemia, offering a more accurate, non-animal testing platform.

Oxford joins £15.9m national initiative to transform cancer research using live human tissue models

The University of Oxford is part of a £15.9 million UK-wide programme to develop human tumour tissue models, improving cancer research, accelerating drug discovery and reducing reliance on animal testing.

UK government urged to act on radon exposure

The UK Radon Association is urgently calling on the Government to launch a national campaign addressing exposure to radon gas, an invisible, cancer-causing threat responsible for thousands of preventable lung cancer cases across the UK.

New drug targets tumour defences and reverses chemotherapy resistance

Researchers at King’s College London have developed a novel daily pill, KCL‑HO‑1i, that turns off tumour‑guarding macrophages and boosts chemotherapy effectiveness.

Hidden DNA mutations in healthy people may reveal how cancer starts

Scientists using TwinsUK data and ultra‑precise DNA sequencing have uncovered rare mutations in healthy tissue that could help explain how cancer develops early in life.

NHS launches AI trial to diagnose prostate cancer up to a month faster

The NHS is trialling an AI-powered “one-day diagnostics” pathway for prostate cancer across up to 15 hospitals, aiming to slash diagnostic waiting times by weeks.

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