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Diseases & Conditions

The burden of TB amid the climate crisis

Extreme weather events, the increasing threat of antimicrobial resistance, and other global challenges are impacting the prevalence and fight against tuberculosis. Open Access Government examines the burden of TB, looking at the origins and drivers of this ubiquitous disease

Irregular sleep patterns linked to risk of 172 diseases, study finds

A major UK Biobank study shows that inconsistent sleep timing, not just sleep duration, is associated with increased risk for 172 diseases, including liver cirrhosis and cardiovascular conditions.

Study links COVID-19 pandemic to accelerated brain ageing

New research from the University of Nottingham shows the COVID-19 pandemic may have accelerated brain ageing by over five months, even in people who were never infected, due to stress and lifestyle changes.

Long-term air pollution exposure increases dementia risk, study finds

A University of Cambridge study reveals that prolonged outdoor air pollution exposure is associated with a significantly increased risk of developing dementia.

Dementia takes 3.5 years to diagnose after symptoms begin

A UCL-led study finds dementia diagnoses are delayed by an average of 3.5 years after symptoms appear, with even longer waits for early-onset cases.

£40m funding boost to advance autism, ADHD, and neurodevelopmental treatments

A major £40 million investment will drive pioneering research at the University of Edinburgh, aiming to transform diagnosis and treatment for conditions such as autism, fragile X syndrome, and ADHD.

PFAS exposure linked to 31% higher risk of developing type 2 diabetes

New research shows that exposure to PFAS chemicals may increase the risk of type 2 diabetes by disrupting metabolism and affecting blood sugar regulation.

How toxic tau spreads in progressive supranuclear palsy: New research reveals synaptic link

UK Dementia Research Institute scientists reveal how toxic tau spreads between neurons in PSP, causing synapse loss.

UK Government announces comprehensive ME/CFS support strategy across NHS

The UK Government has unveiled an enhanced support plan for people with ME/CFS, including NHS staff training, public awareness campaigns, and up to £200,000 in grants per research project.

Music therapy may reduce distress in people living with dementia, study finds

Groundbreaking research has revealed that music therapy could be a game-changer in the treatment of dementia, potentially reducing distress.

£2.7m Liverpool-led trial to explore vagus nerve stimulation for drug-resistant epilepsy

The University of Liverpool is leading a £2.7 million clinical trial to investigate vagus nerve stimulation as a treatment for people with drug-resistant epilepsy.

Detection dogs show high accuracy in identifying Parkinson’s disease from skin swabs

A University of Bristol study finds trained detection dogs can identify Parkinson's disease with up to 98% accuracy by smelling skin swabs, offering promise for early, non-invasive diagnosis.

Promising Alzheimer’s vaccine enters phase 1 clinical trial to target tau protein

University of New Mexico researchers are launching a phase 1 clinical trial of a novel Alzheimer’s vaccine designed to clear tau protein.

Skin swabs may detect Parkinson’s up to seven years early

A new University of Manchester study finds that analysing skin sebum via non-invasive swabs can identify Parkinson's biomarkers up to seven years before motor symptoms emerge, offering hope for earlier detection and intervention.

New study reveals the four early warning signs of Alzheimer’s

UCLA researchers have uncovered four distinct diagnostic pathways leading to Alzheimer's disease by analysing data from 25,000 patients.

Weekly Levodopa-Carbidopa injection could revolutionise Parkinson’s care

A University of South Australia team has developed a weekly biodegradable injection of levodopa and carbidopa, offering seven-day release to ease dosing and boost adherence for Parkinson’s patients.

OTOF gene therapy restores hearing in deaf patients

A first-in-patient trial using AAV-based OTOF gene therapy, led by Karolinska Institutet and Chinese hospitals, restored hearing (improving from 106 dB to 52 dB) in 10 individuals aged 1–24.

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