Lee is a registered dietitian and worked as a dietitian in the National Health Service for ten years, with extensive experience of community health promotion and cardiovascular health
Lee moved to research in 2000 and has since published over 100 peer-reviewed publications, mainly in the areas of dehydration and nutrition of older people and the effects of dietary change on health. Lee is a member of the World Health Organization Nutrition Guidance Expert Advisory Group (NUGAG) on Diet and Health, which has recently produced guidance on sodium and potassium intakes. She is also an editor of the Cochrane Heart Group.