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Acute myeloid leukaemia (AML) and cytarabine pharmacogenomics
Professor Jatinder Lamba from the Department of Pharmacotherapy and Translational Research gives an in-depth perspective on acute myeloid leukaemia (AML) and cytarabine pharmacogenomics
Acute myeloid leukaemia (AML) is the cancer of the myeloid precursor stem cells characterised by the appearance of immature, abnormal myeloid cells in bone marrow and other...
Acute myeloid leukaemia (AML)
Acute myeloid leukaemia (AML), a form of blood cancer is placed into the spotlight by Open Access Government
Acute myeloid leukaemia (AML) is a form of blood cancer, which affects the white blood cells known as myeloid cells. It is a rapidly progressing form of leukaemia. Blood cells are formed...
Living with Leukaemia
Bethany Torr, campaigns and advocacy officer at Leukaemia Care introduces ‘Leukaemia’ and its different forms and explains how people live with the disease
Leukaemia’ is an umbrella term for cancers of the white blood cells – ‘leuk’ means white and ‘aemia’ refers to a condition of the blood. 26 people are...
Fostering and supporting excellence in clinical pharmacy practice
Islam Elkonaissi and Zahra Laftah from the UKCPA explore the British model of supporting excellence in clinical pharmacy practice
In the UK, evidence that pharmacists can provide better clinical outcomes and more efficient, consistent and sustainable services for patients, is increasing. In this article, key themes are discussed to showcase...
Dose-finding trials: why not to use algorithmic designs
Prof Thomas Jaki from the Medical and Pharmaceutical Statistics Research Unit at Lancaster University sheds light on dose-finding trials
Tumour-host interactions, paediatric sarcomas, and cancer progression
Ivan Stamenkovic, professor of experimental pathology at the University of Lausanne underlines research taking place around cancer progression
Cancer progression, meaning the evolution of localised tumour growth to an invasion of adjacent tissue and dissemination to distant organs is a complex process that is intimately related to interactions between tumour...
University of California scientists target glioblastoma with stem cell research
Targeted stem cell research at the University of California, Irvine could one day eradicate glioblastoma brain tumours, explains John Lowengrub
Personalising antibody directed therapy in Acute Myeloid Leukaemia (AML)
Professor Jatinder Lamba from the Department of Pharmacotherapy and Translational Research explores the current progress in Acute Myeloid Leukaemia (AML)
Effective prevention and control of infectious diseases
David Partridge from the British Infection Association provides a comprehensive overview of effective infection prevention and control in the UK today
NHS approves new ‘life extending’ lung cancer drug
After extended campaigns from charities and prominent figures, a lung cancer drug said to extend the life of sufferers has been made available on the NHS
The nivolumab lung cancer drug is already available in Scotland for those with advanced lung cancer who are already undergoing chemotherapy.
The immunotherapy treatment stimulates...
Biomedical research: crossing discipline borders
Biomedical research crosses borders of disciplines to help shape new imaging approaches, as scientists from Technical University of Munich explain
Targeting stem cell transdifferentiation could eradicate glioblastoma
John Lowengrub and colleagues provide insight into the challenge to eradicate glioblastoma and the use of stem cell transdifferentiation.
Huaming Yan1,7, Mónica Romero-López2, Lesly I. Benitez4, Kaijun Di4,9, Hermann B. Frieboes5,6, Christopher C. W. Hughes2,4,7,8, Daniela A. Bota8,9,10, Vittorio Cristini11, John Lowengrub1,2,7,8
1 Dept. of Mathematics, University of California, Irvine, CA 92697
2 Dept....
Photodynamic Therapy – radiotherapy for the 21st Century
Photodynamic Therapy is a treatment that combines a photosensitizing drug, visible light and oxygen to kill cancer cells. Professor Eli Glatstein explains
Image-guided surgery as an emerging treatment for lung cancer
Sumith A Kularatne, Vice President of Research & Development at On Target Laboratories discusses the scope of image-guided surgery in treating lung cancer
Identifying novel biomarkers for drug-induced kidney injury
The European Federation of Pharmaceutical Industries and Associations (EFPIA) explain how SAFE-T DIKI is advancing research into drug-induced kidney injury
Disease-associated myosteatosis in people with cancer: Can it be treated?
Can we prevent the muscle loss associated with some cancers? Dr Vera Mazurak at the University of Alberta is looking into one method of treating myosteatosis
Pathological fat infiltration into muscle is a feature of disease-induced muscle loss that significantly associates with shorter survival in people with cancer. Fat is...
Cancer research and training take centre stage in NCI’s work
Open Access Government spoke to the National Cancer Institute’s Dr S Percy Ivy about cancer research and training and the importance of clinical trials
The National Cancer Institute (NCI) is one of 27 institutes that make up the National Institutes of Health (NIH). The NCI is the US federal government’s...
How far have we come on treating gynaecological cancer?
New avenues are opening up for treatment of gynaecological cancer, Professor Gunnar Kristensen of Oslo University Hospital explains to Open Access Government
Surgery remains an important step in the treatment of ovarian cancer. Two earlier randomised studies revealed the same survival rates for patients who had surgery as the first...
Treatments for prostate cancer: Pros and cons
Dr Sumith A Kularatne, vice-president of R&D at On Target Laboratories, explores the pros and cons of various existing treatments for prostate cancer
Prostate cancer (PCa) is the second leading cause of cancer-related deaths in men, with about 1.1 million new cases and approximately 307,000 fatalities per year globally. This...
Regional organisation and the Orkdal model of cancer care
The Orkdal model of cancer care rests on collaboration between specialist oncology and community care in palliative treatment, as Anne Kari Knudsen explains
The Norwegian Orkdal model of cancer care has been called “the future of cancer care”. The aim is to develop and implement a model for optimal cancer...
