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New developments in the treatment of ovarian cancer
Gunnar Kristensen, from the Department of Gynaecologic Oncology at Oslo University Hospital, looks at new strategies for the treatment of ovarian cancer.
It is recognised that the disease we usually call ovarian cancer can originate from either the ovaries, the fallopian tube (the organ bringing the eggs from the ovaries...
A spatio-temporal mathematical model for cancer
Zhihui Wang1,2 and Vittorio Cristini1,2 outline how they have developed a model to help predict cancer treatment outcomes…
The physical properties of a tumour’s microenvironment influence a drug’s ability to penetrate and kill tumour cells. Some of these properties can be potential obstructions to drug diffusion, increasing the tumour’s resistance...
Preventing and reducing HCAIs
Professor Alan Johnson, Head of the Department of Healthcare-Associated Infection and Antimicrobial Resistance at Public Health England, explains to Editor Laura Evans about healthcare association infections and how they link to antibiotic resistance
Healthcare-Associated Infections (HCAIs) are infections that are contracted within healthcare settings, such as hospitals and care homes. They...
Mathematical Modeling of Drug Delivery via Nanoparticles in Cancer Treatment
Cancer is a complex and heterogeneous disease. Despite all efforts to fight cancer, it continues to impact every segment of society. For example, many patients fail conventional cancer therapies, including chemotherapy, radiation, and surgery; and it is still difficult for physicians to predict a treatment outcome with certainty.
Nanotherapy and its role in multiple myeloma treatment
A new class of nanotherapy blockades the genetic drive for multiple myeloma progression. Gregory M. Lanza and Michael H Tomasson, of Department of Medicine, Washington University School of Medicine explain...
Multiple myeloma is malignancy of plasma cells that reside in the bone marrow and normally function as part of our immune defence...
Development of multiple drug resistance (MDR)
Terra G. Arnason and Troy A.A. Harkness from the Departments of Medicine, and Anatomy and Cell Biology at the University of Saskatchewan detail current strategies to prevent or reverse multiple drug resistant malignancy…
Multiple drug resistance (MDR) can be present from the outset (inherent) or develop (acquired) in response to...
Molecular and cellular mechanisms of cancer
Professor Wen Jiang, Dr Andrew Sanders and Dr Lin Ye from the Cardiff China Medical Research Collaborative, Cardiff University School of Medicine highlight the work being done to combat cancer and develop new treatments…
Cancer presents a serious issue worldwide for healthcare systems and results in substantial morbidity and mortality for...
Platelets in hemostasis and thrombosis – finding the right balance
Nucleated blood platelets are produced by their bone marrow resident precursors, the megakaryocytes, in a unique process in mammalian physiology. Terminally differentiated, polyploid megakaryocytes are the largest cells in the bone marrow evolving from hematopoietic stem cells. Megakaryocytes are localised in close proximity to sinusoidal blood vessels and convert...
Research at Oslo University Hospital in the field of Gynaecologic cancer
Oslo University Hospital (OUS) is a big hospital formed by the merger of 4 hospitals. The State Hospital, the Norwegian Radium Hospital, Ullevaal Hospital and Aker Hospital. It serves as a local hospital for about 600,000 inhabitants and as a referral centre for about 2.8 million people. As a...
Improved cancer care: Integrating palliative care and oncology
Norwegian cancer researchers launch a project to improve care for cancer patients with a limited life expectancy
Europe has about 3.5 million new cancer cases per year, and the number is rising. Advances in treatment options have led to more patients getting cured and prolonged survival for those with incurable...
Reducing the burden of cancer
AG highlights the work of the National Cancer Institute (NCI), to reduce and treat cancer.
The National Cancer Institute (NCI) is the U.S. Federal government’s primary agency for cancer research and training. As part of the National Institutes of Health (NIH) they coordinate with the National Cancer Programme, which conducts...
Prediction of cancer treatment outcome using physics
Vittorio Cristini1,2, Eugene J. Koay3, and Zhihui Wang1,2
1Department of NanoMedicine and Biomedical Engineering, University of Texas Medical School at Houston, Houston, TX 77054, USA
2Brown Foundation Institute of Molecular Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA
3Department of Radiation Oncology, University of Texas MD Anderson Cancer...
Million dollar question in prostate cancer research
Owen Sharp, CEO at Prostate Cancer UK sheds light on the important work that’s being done to better diagnose and treat prostate cancer…
Most prostate cancers aren’t a problem. In fact, for many the problems only come from diagnosing and treating them. These are the prostate cancers a surgeon once...
Muscling in on myopenia and myosteatosis
The relationship between body composition and risk of disease has become more clearly understood in recent years, as the technology available to non-invasively quantify components of body mass has improved. Image-based approaches specifically and precisely quantify muscle and fat, while having the capacity to also reveal additional features such...
The million dollar question in prostate cancer research
Owen Sharp, CEO at Prostate Cancer UK sheds light on the important work that’s being done to better diagnose and treat prostate cancer
Most prostate cancers aren’t a problem. In fact, for many, the problems only come from diagnosing and treating them. These are the prostate cancers a surgeon once...
Skin cancer: deadly but preventable
Jon Pleat MA DPhil FRCS(Plast), Plastic Surgeon and Scientific Advisor at SCaRF details the risks of skin cancer and how it can be prevented…
Skin cancer is the most common form of cancer globally. There are more than 80,000 deaths a year from its different forms. Within the UK, the incidence...
Cancer imperialism – how to diagnose bone metastases?
Cancer is an unreliable disease. Just as you think you are familiar with it and can begin treating and hopefully curing it, it is no longer as you thought it was.
It has coloured its hair, carries other garments, or has changed its lifestyle making it unrecognisable and impossible...
Skin cancer: deadly but preventable
Jon Pleat MA DPhil FRCS(Plast), Plastic Surgeon and Scientific Advisor at SCaRF details the risks of skin cancer and how it can be prevented
Skin cancer is the most common form of cancer globally. There are more than 80,000 deaths a year from its different forms. Within the UK, the incidence...
