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Sepsis, bacteria in blood. 3D illustration showing rod-shaped bacteria in blood with red blood cells and leukocytes

Sepsis and the killer platelets

Dermot Cox BSc, PG Dip Ed, PhD, Pharmacology Lead from the School of Pharmacy and Biomolecular Sciences – RCSI University of Medicine & Health Sciences, discusses sepsis and the killer platelets.
water bottles on an automated conveyor belt, Bottled water production line

Nanoplastics found in bottled water raise concerns over human health

Microplastics have become a global environmental concern, with these tiny particles infiltrating polar ice, soil, drinking water, and food we consume.
asbestos chrysotile fibers that cause lung disease, COPD, lung cancer, mesothelioma

Lessons from Libby: Understanding the impact of asbestos exposure

Jean C. Pfau, Scientific Consultant at the Center for Asbestos Related Disease, shares the devasting story of asbestos exposure occurring in a Rocky Mountain town of Montana and the critical lessons that can be learned from this event.
Mature man helps younger man verbalize problems in therapy

Breaking the stigma: Men’s mental health matters

Dr Deborah Lee from Dr Fox Online Pharmacy discusses men’s mental health, including common barriers to seeking help and the measures needed to improve overall awareness and support.
Stem cells, cancer survival rates

Secarna aims to expand the therapeutic toolbox against cancer

Current oncology treatments have significantly improved cancer survival rates, but more effective and safer therapeutics are needed.
Cropped shot of a female nurse hold her senior patient's hand. Giving Support. Doctor helping old patient with Alzheimer's disease. Female carer holding hands of senior man

Supporting stroke patients: The societal and healthcare burden of stroke

Elliot Grantham, Market Development Manager at Medtronic, discusses the challenges in stroke care and how it could be improved for stroke patients.
Figure 1. Two routes of brain infection by which SARS-CoV-2 may enter the hypothalamus and infect GnRH neurons. The virus attaches to and enters cells harbouring surface receptors such as ACE2 (black spanner-like symbol) or NRP1 (red cylinder). GnRH neurons exhibit both, which might increase their vulnerability. A. The haematological route, whereby the respiratory virus (white spheres) makes its way through the lungs into the bloodstream (dark red), and thence into the median eminence (ME), a part of the hypothalamus that harbours ”fenestrated” or leaky blood vessels. The virus may affect a number of different cell types locally, including GnRH neurons (green), whose secretory terminals approach the fenestrated vessels, and tanycytes (grey), whose processes control this secretion and also transport other bloodborne hormones and other substances into the brain. Once inside the brain ventricles (V), fluid-filled canals within the brain, the virus can also travel to other areas. B. The olfactory route, whereby the virus enters the olfactory bulb (OB) of the brain directly from the nose across the bony cribriform plate by means of nerve bundles or infected olfactory neurons and other cell types. GnRH neurons, which are born in the nasal epithelium during the embryonic period and migrate into the brain along these nerve bundles to their final positions, still maintain a connection with their birthplace, and could be thus be infected directly or indirectly through olfactory neurons or other cells. GnRH neurons also project to parts of the brain involved in higher functions such as cognition, potentially contributing to long-COVID symptoms such as “brain fog”.

Brain infection by SARS-CoV-2: Lifelong consequences

The WATCH team, founded to elucidate the role played by specialized brain cells called tanycytes in various physiological processes, has been investigating how and where the SARS-CoV-2 virus infects the brain, and some long-term consequences of this neuro-invasion.
Psoriasis biopsy

Understanding psoriasis: Symptoms, causes, and treatments

Psoriasis is a chronic immune-mediated inflammatory disease that can impact sufferers’ mental and physical health. We discuss the complexity of the condition as well as the emergence of effective treatments with the national UK charity The Psoriasis Association.
White blood cells with nucleus and granule . Transparency cell membrane . Medical and science concept background . 3D render .

Personalised treatment shows promising results in leukaemia trial

A new personalised treatment has been discovered for the most common form of adult leukaemia, which has been found to help patients live longer.
Vaccine in researcher hands

Can an immunisation technique speed up vaccine development?

Researchers in Germany have pioneered a system for displaying epitopes in mammal cells, potentially revolutionising immunisation studies.
Promoting regular exercise to protect brain health

Promoting regular exercise to protect brain health

Regular exercise is a critical step in maintaining healthy physiology and ensuring healthy aging. However, there are many diseases and conditions that make exercise inaccessible or reduce its efficacy. The Wessells lab studies exercise and the pathways it works through to identify key molecules required for a proper exercise response.
women in bed blowing nose with a cold

Which natural remedies will help you battle a cold this year?

With the days getting colder and colder and the flu season approaching, several health professionals give their insight and recommendations on natural remedies for illnesses.
Tissue from sellar lesion, microscopy show multiple wet keratin, basaloid appearing cells, inflammatory cells and giant cells. Diagnosis Craniopharyngioma.

Current and future therapy for BRAF-mutant pediatric glioma

Professor Peter J. Houghton from the Greehey Children’s Cancer Research Institute discusses new approaches to pediatric cancer treatment specifically for BRAF-mutant pediatric glioma.
Abs Lactobacillus Bulgaricus Bacteria’

Sepsis survivors: Improving long-term health outcomes post sepsis

Michael Wong and Amy Campbell from the Physician-Patient Alliance for Health & Safety reflect on the fourth World Sepsis Congress discussion, which focused on ways to improve long-term health outcomes post sepsis.
Elderly Man Inserting His Hearing Aid

Hearing loss: Ageing and noise exposure are the two major causes

Dr Tracey Pollard from RNID, the charity which supports the 12 million people in the UK who are deaf, have hearing loss or tinnitus, talks us through the causes and impact of hearing loss and how RNID is working to improve research and related treatments in this field.
People, health care and problem concept - unhappy mid adult man suffering from knee ache at home

Understanding osteoarthritis: Causes, symptoms, and treatment options

With ten million people in the UK alone suffering from osteoarthritis, Dr Deborah Lee explains the prevalence of the condition, the common risk factors, and preventative measures.
DNA structure, NCD

Effective vaccines for non-communicable diseases – A pipe dream?

Markus Mandler, Founder and CEO of Tridem Bioscience, explains how the company’s cutting-edge vaccine platform is revolutionising treatment approaches and vaccines for non-communicable diseases (NCDs).
Kidney disease

Understanding polycystic kidney disease (PKD) and its challenges

Polycystic kidney disease is a genetic disorder that lacks a cure and can significantly impact an individual’s quality of life. We spoke to the American Kidney Fund regarding the challenges of diagnosis and disease management.
The link between chemicals in our environment and Parkinson's disease

The link between chemicals in our environment and Parkinson’s disease

In 1980, hundreds of individuals reported to emergency clinics in Northern California complaining of tremors, motility problems, and mild cognitive deficits - all classic signs of Parkinson’s disease (PD)
Figure 1: Immunofluorescent image of OVCAR3 cells in culture showing that cells are at different stages of the cell cycle. P53 (green) is nuclear in all cells that are not dividing, including PGCCs that are multinuclear (a) and (b). PGCC during abnormal cytokinesis (c). P53 is redistributed in cells undergoing normal mitosis where the condensed chromosomes are either at the midbody (d) or are undergoing cytokinesis (e). (1)

Controlling ovarian cancer: An introduction to detection and treatment

With current strategies proving inadequate, what needs to be done is to further the research into detecting, treating, and controlling ovarian cancer.

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