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cellular pathways

Intramembrane proteases: Regulators of cellular pathways

Prof Dr Regina Fluhrer from Biomedical Center (BMC), Ludwig Maximilians University of Munich (LMU) & German Center for Neurodegenerative Diseases (DZNE) shares her expertise on the field of intramembrane proteases, focussing on regulation of cellular pathways
neurological disease

Reducing the burden of neurological disease: A focus on stroke research

Open Access Government looks at the wider work of The National Institute of Neurological Disorders and Stroke in the U.S. when it comes to reducing the burden of neurological disease and how they are supporting stroke research
Hydrogen-powered trains

Hydrogen-powered trains: The remaining challenges for innovators

Rosie Hardy and Frank Harner at Withers & Rogers explore the exciting world of hydrogen-powered trains and detail what the remaining challenges for innovators are in this area
stem cells

From wheelchair to high heels: Realising the potential of stem cells

Dr Michael A Rudnicki, CEO & Scientific Director at the Stem Cell Network gives an expert view on a new era in health care, powered by stem cells
RELEVANCE project

Relevance Project – red cell life-spans

The Relevance consortium project researches the regulation of red cell life-spans, erythropoiesis, survival, senescence and clearance RELEVANCE is an international consortium of thirteen partners representing academic research centres, diagnostic labs, blood supply centres, and small industries that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood...

Imaging cerebral blood flow with single capillary resolution

Experts from the European Laboratory for Non-Linear Spectroscopy and the Neuroscience Institute reflect on cerebral blood flow (CBF)
cancer

Understanding cancer through molecular cell biology

Progress in Targeted Therapy and Immunotherapy of Cancer Requires Rethinking of European Reimbursement Practices for Mutation Testing
chemotherapy predicting cancer treatment outcome

Tissue-scale factors in predicting cancer treatment outcome

Zhihui Wang and Vittorio Cristini provide evidence that could improve the success of treatment plans and make predicting cancer treatment outcome easier Current processes for creating cancer treatment plans are primarily based on empirical data from clinical trials, consensus expert panel guidelines, and limited laboratory-based testing. Physicians still face major...
parkinson's disease

Restoring dopaminergic nerve cells in Parkinson’s disease

Dr Mehis Pilv, CEO and business development lead at Genecode, discusses the strides being made in Parkinson's disease research Parkinson's disease is a slow but progressive neurodegenerative disorder. About 1% of people aged above 50 are affected worldwide. In Europe alone 1.2 million people suffer from Parkinson's disease, 127,000 of whom...
umbilical cord blood benefits newborn baby

Umbilical cord blood: A life enhancer for all babies

Judith Mercer and Debra-Erickson Owens have found positive changes after a short delay in cord clamping, indicating the benefits of umbilical cord blood When cord clamping is delayed at birth (DCC), an infant receives a placental transfusion and benefits from a 30% increase in blood volume and a 50% increase...
Reducing HCAIs on hospital wards

Preventing and reducing HCAIs

Professor Alan Johnson, Head of the Department of Healthcare-Associated Infection and Antimicrobial Resistance at Public Health England, explains to Editor Laura Evans about healthcare association infections and how they link to antibiotic resistance Healthcare-Associated Infections (HCAIs) are infections that are contracted within healthcare settings, such as hospitals and care homes. They...

Molecular and cellular mechanisms of cancer

Professor Wen Jiang, Dr Andrew Sanders and Dr Lin Ye from the Cardiff China Medical Research Collaborative, Cardiff University School of Medicine highlight the work being done to combat cancer and develop new treatments… Cancer presents a serious issue worldwide for healthcare systems and results in substantial morbidity and mortality for...
NCI

Reducing the burden of cancer

AG highlights the work of the National Cancer Institute (NCI), to reduce and treat cancer. The National Cancer Institute (NCI) is the U.S. Federal government’s primary agency for cancer research and training. As part of the National Institutes of Health (NIH) they coordinate with the National Cancer Programme, which conducts...
Cancer

Prediction of cancer treatment outcome using physics

Vittorio Cristini1,2, Eugene J. Koay3, and Zhihui Wang1,2 1Department of NanoMedicine and Biomedical Engineering, University of Texas Medical School at Houston, Houston, TX 77054, USA 2Brown Foundation Institute of Molecular Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA 3Department of Radiation Oncology, University of Texas MD Anderson Cancer...
Sickle Cell research, Ireland

Importance of sickle cell genetic screening in Ireland

Lora Ruth Wogu, CEO and Founder of Sickle Cell and Thalassaemia Ireland, outlines what sickle cell disease and thalassaemia are and why screening in Ireland is fundamental Sickle cell anaemia and thalassaemia disease are 2 of the major genetic blood disorders that affect the red blood cells. Sickle cell disease...
Diana Agacy, Blood Transfusion Nurse Practitioner and Phlebotomy Manager at University Hospital Southampton NHS Foundation gives an overview of the importance of patient safety during blood transfusions…

Practising patient safety during blood transfusions

Diana Agacy, Blood Transfusion Nurse Practitioner and Phlebotomy Manager at University Hospital Southampton NHS Foundation gives an overview of the importance of patient safety during blood transfusions. As a transfusion practitioner, the main aspect of my role is to educate healthcare professionals in safe transfusion practice and the first thing...
stem cell

Challenging the stem cell convention

Professor Alan Clarke, Director of the European Cancer Stem Cell Research Institute gives an overview of how cancer stem cells differ from the conventional stem cell. Cancer remains one of the major challenges in terms of life expectancy and is recognised as the second largest cause of mortality within the...
stem cells

Stem cells and immunity

From stem cell biology to tissue mending In the last 25 years, tremendous advances have been made in the identification and generation of stem cells (SC) from diverse organisms, generating a wealth of knowledge in various fields from embryology to development. SC not only have the ability to differentiate into...
antimalarial

Scientists find new antimalarial drug targets

Researchers have discovered new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets
Medicine doctor touching electronic medical record on tablet. DNA. Digital healthcare and network connection on hologram modern virtual screen interface, medical technology and network concept.

NHS patients to benefit from faster access to innovative medical technologies

NHS patients in England are set to gain quicker access to the latest and most innovative medical technologies, thanks to new plans proposed by NHS England and the National Institute for Health and Care Excellence (NICE).

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