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Intramembrane proteases: Regulators of cellular pathways
Prof Dr Regina Fluhrer from Biomedical Center (BMC), Ludwig Maximilians University of Munich (LMU) & German Center for Neurodegenerative Diseases (DZNE) shares her expertise on the field of intramembrane proteases, focussing on regulation of cellular pathways
Reducing the burden of neurological disease: A focus on stroke research
Open Access Government looks at the wider work of The National Institute of Neurological Disorders and Stroke in the U.S. when it comes to reducing the burden of neurological disease and how they are supporting stroke research
Hydrogen-powered trains: The remaining challenges for innovators
Rosie Hardy and Frank Harner at Withers & Rogers explore the exciting world of hydrogen-powered trains and detail what the remaining challenges for innovators are in this area
From wheelchair to high heels: Realising the potential of stem cells
Dr Michael A Rudnicki, CEO & Scientific Director at the Stem Cell Network gives an expert view on a new era in health care, powered by stem cells
Relevance Project – red cell life-spans
The Relevance consortium project researches the regulation of red cell life-spans, erythropoiesis, survival, senescence and clearance
RELEVANCE is an international consortium of thirteen partners representing academic research centres, diagnostic labs, blood supply centres, and small industries that combines basic and translational research to improve prognostic, diagnostic and therapeutic approaches on red blood...
Imaging cerebral blood flow with single capillary resolution
Experts from the European Laboratory for Non-Linear Spectroscopy and the Neuroscience Institute reflect on cerebral blood flow (CBF)
Understanding cancer through molecular cell biology
Progress in Targeted Therapy and Immunotherapy of Cancer Requires Rethinking of European Reimbursement Practices for Mutation Testing
Tissue-scale factors in predicting cancer treatment outcome
Zhihui Wang and Vittorio Cristini provide evidence that could improve the success of treatment plans and make predicting cancer treatment outcome easier
Current processes for creating cancer treatment plans are primarily based on empirical data from clinical trials, consensus expert panel guidelines, and limited laboratory-based testing. Physicians still face major...
Restoring dopaminergic nerve cells in Parkinson’s disease
Dr Mehis Pilv, CEO and business development lead at Genecode, discusses the strides being made in Parkinson's disease research
Parkinson's disease is a slow but progressive neurodegenerative disorder. About 1% of people aged above 50 are affected worldwide. In Europe alone 1.2 million people suffer from Parkinson's disease, 127,000 of whom...
Umbilical cord blood: A life enhancer for all babies
Judith Mercer and Debra-Erickson Owens have found positive changes after a short delay in cord clamping, indicating the benefits of umbilical cord blood
When cord clamping is delayed at birth (DCC), an infant receives a placental transfusion and benefits from a 30% increase in blood volume and a 50% increase...
Preventing and reducing HCAIs
Professor Alan Johnson, Head of the Department of Healthcare-Associated Infection and Antimicrobial Resistance at Public Health England, explains to Editor Laura Evans about healthcare association infections and how they link to antibiotic resistance
Healthcare-Associated Infections (HCAIs) are infections that are contracted within healthcare settings, such as hospitals and care homes. They...
Molecular and cellular mechanisms of cancer
Professor Wen Jiang, Dr Andrew Sanders and Dr Lin Ye from the Cardiff China Medical Research Collaborative, Cardiff University School of Medicine highlight the work being done to combat cancer and develop new treatments…
Cancer presents a serious issue worldwide for healthcare systems and results in substantial morbidity and mortality for...
Reducing the burden of cancer
AG highlights the work of the National Cancer Institute (NCI), to reduce and treat cancer.
The National Cancer Institute (NCI) is the U.S. Federal government’s primary agency for cancer research and training. As part of the National Institutes of Health (NIH) they coordinate with the National Cancer Programme, which conducts...
Prediction of cancer treatment outcome using physics
Vittorio Cristini1,2, Eugene J. Koay3, and Zhihui Wang1,2
1Department of NanoMedicine and Biomedical Engineering, University of Texas Medical School at Houston, Houston, TX 77054, USA
2Brown Foundation Institute of Molecular Medicine, University of Texas Medical School at Houston, Houston, TX 77030, USA
3Department of Radiation Oncology, University of Texas MD Anderson Cancer...
Importance of sickle cell genetic screening in Ireland
Lora Ruth Wogu, CEO and Founder of Sickle Cell and Thalassaemia Ireland, outlines what sickle cell disease and thalassaemia are and why screening in Ireland is fundamental
Sickle cell anaemia and thalassaemia disease are 2 of the major genetic blood disorders that affect the red blood cells. Sickle cell disease...
Practising patient safety during blood transfusions
Diana Agacy, Blood Transfusion Nurse Practitioner and Phlebotomy Manager at University Hospital Southampton NHS Foundation gives an overview of the importance of patient safety during blood transfusions.
As a transfusion practitioner, the main aspect of my role is to educate healthcare professionals in safe transfusion practice and the first thing...
Challenging the stem cell convention
Professor Alan Clarke, Director of the European Cancer Stem Cell Research Institute gives an overview of how cancer stem cells differ from the conventional stem cell.
Cancer remains one of the major challenges in terms of life expectancy and is recognised as the second largest cause of mortality within the...
Stem cells and immunity
From stem cell biology to tissue mending
In the last 25 years, tremendous advances have been made in the identification and generation of stem cells (SC) from diverse organisms, generating a wealth of knowledge in various fields from embryology to development. SC not only have the ability to differentiate into...
Scientists find new antimalarial drug targets
Researchers have discovered new processes that allow malaria parasites to escape red blood cells and infect other cells, offering potential new treatment targets
NHS patients to benefit from faster access to innovative medical technologies
NHS patients in England are set to gain quicker access to the latest and most innovative medical technologies, thanks to new plans proposed by NHS England and the National Institute for Health and Care Excellence (NICE).