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All available data shows that, despite a better understanding of the biology of tumour cells, the treatment of most cancers has not significantly changed for the past three decades. For the main types of cancer, survival rates for people diagnosed when their tumours were in an advanced stage has changed...

Understanding liver cancer development in Europe: Novel mouse models for pre-clinical trials. Today, liver cancer – also called hepatocellular carcinoma (HCC) – reflects the 3rd most common cause for cancer related death world-wide with approximately 800.000 deaths per year. In stray African or Asian countries HCC has become the most common...

Hepatocarcinogenesis and future challenges: Pre-clincial models for virus- or high fat diet-induced liver cancer.