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Photodynamic therapy and immune response in solid tumours

Photodynamic therapy can stimulate a person’s own immune system to better recognise – and fight – cancer tumours, say Mary Potasek, PhD and Karl Beeson, PhD of Simphotek and Theresa M Busch, PhD of the Department of Radiation Oncology, University of Pennsylvania.
Mature woman brushing her hair at home

How does our diet and lifestyle affect our hair growth?

According to hair stylists, 68% of women are unhappy about their hair. How women feel about our hair correlates strongly with our feelings. The most common complaints are that our hair is 'too dry', 'it's falling out', or it 'grows too slowly'.
Medical illustration series about abstract human.The nervous system.

Hydrogen therapy for liver surgery: Current insights and future prospects in ischemia-reperfusion injury

Prof. Giovanni Brandi1,2 and Dr. Simona Tavolari1 of the 1 Medical Oncology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; 2Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy, discuss ischemia-reperfusion injury in hepatic surgery, and the potential to prevent it through hydrogen-therapy.
Antibody binding to human cell receptors is a crucial aspect of the immune response and plays a fundamental role in various physiological processes, including immune defense, signaling, and regulation of cellular functions. Antibodies, also known as immunoglobulins, are proteins produced by the immune system in response to the presence of foreign substances, such as pathogens or abnormal cells.

High-resolution snapshots of antibody repertoires as potential correlates of protection

Klaus Eyer from ETH Zurich describes high-resolution snapshots of antibody repertoires as potential correlates of protection.
Vape teenager. Young pretty white girl in blue cap and green jacket smoking an electronic cigarette opposite brick wall on the street in the spring.

The immediate impact of e-hookah vaping on vascular health

With the rise of vaping continuing to increase, electronic (e-) hookahs have been advertised as a safer tobacco alternative, but it’s not all it seems.
Cancer cells in human body, conceptual 3d illustration

Unraveling the potential of antisense therapies to target neuropilin 1 in the fight against...

Secarna Pharmaceuticals, the next-generation antisense drug discovery and development company, is developing novel approaches to successfully target Neuropilin 1 (NRP1), a promising target for the treatment of cancer.
Sepsis, bacteria in blood. 3D illustration showing rod-shaped bacteria in blood with red blood cells and leukocytes

Sepsis and the killer platelets

Dermot Cox BSc, PG Dip Ed, PhD, Pharmacology Lead from the School of Pharmacy and Biomolecular Sciences – RCSI University of Medicine & Health Sciences, discusses sepsis and the killer platelets.
water bottles on an automated conveyor belt, Bottled water production line

Nanoplastics found in bottled water raise concerns over human health

Microplastics have become a global environmental concern, with these tiny particles infiltrating polar ice, soil, drinking water, and food we consume.
asbestos chrysotile fibers that cause lung disease, COPD, lung cancer, mesothelioma

Lessons from Libby: Understanding the impact of asbestos exposure

Jean C. Pfau, Scientific Consultant at the Center for Asbestos Related Disease, shares the devasting story of asbestos exposure occurring in a Rocky Mountain town of Montana and the critical lessons that can be learned from this event.
Mature man helps younger man verbalize problems in therapy

Breaking the stigma: Men’s mental health matters

Dr Deborah Lee from Dr Fox Online Pharmacy discusses men’s mental health, including common barriers to seeking help and the measures needed to improve overall awareness and support.
Stem cells, cancer survival rates

Secarna aims to expand the therapeutic toolbox against cancer

Current oncology treatments have significantly improved cancer survival rates, but more effective and safer therapeutics are needed.
Cropped shot of a female nurse hold her senior patient's hand. Giving Support. Doctor helping old patient with Alzheimer's disease. Female carer holding hands of senior man

Supporting stroke patients: The societal and healthcare burden of stroke

Elliot Grantham, Market Development Manager at Medtronic, discusses the challenges in stroke care and how it could be improved for stroke patients.
Figure 1. Two routes of brain infection by which SARS-CoV-2 may enter the hypothalamus and infect GnRH neurons. The virus attaches to and enters cells harbouring surface receptors such as ACE2 (black spanner-like symbol) or NRP1 (red cylinder). GnRH neurons exhibit both, which might increase their vulnerability. A. The haematological route, whereby the respiratory virus (white spheres) makes its way through the lungs into the bloodstream (dark red), and thence into the median eminence (ME), a part of the hypothalamus that harbours ”fenestrated” or leaky blood vessels. The virus may affect a number of different cell types locally, including GnRH neurons (green), whose secretory terminals approach the fenestrated vessels, and tanycytes (grey), whose processes control this secretion and also transport other bloodborne hormones and other substances into the brain. Once inside the brain ventricles (V), fluid-filled canals within the brain, the virus can also travel to other areas. B. The olfactory route, whereby the virus enters the olfactory bulb (OB) of the brain directly from the nose across the bony cribriform plate by means of nerve bundles or infected olfactory neurons and other cell types. GnRH neurons, which are born in the nasal epithelium during the embryonic period and migrate into the brain along these nerve bundles to their final positions, still maintain a connection with their birthplace, and could be thus be infected directly or indirectly through olfactory neurons or other cells. GnRH neurons also project to parts of the brain involved in higher functions such as cognition, potentially contributing to long-COVID symptoms such as “brain fog”.

Brain infection by SARS-CoV-2: Lifelong consequences

The WATCH team, founded to elucidate the role played by specialized brain cells called tanycytes in various physiological processes, has been investigating how and where the SARS-CoV-2 virus infects the brain, and some long-term consequences of this neuro-invasion.
Psoriasis biopsy

Understanding psoriasis: Symptoms, causes, and treatments

Psoriasis is a chronic immune-mediated inflammatory disease that can impact sufferers’ mental and physical health. We discuss the complexity of the condition as well as the emergence of effective treatments with the national UK charity The Psoriasis Association.
White blood cells with nucleus and granule . Transparency cell membrane . Medical and science concept background . 3D render .

Personalised treatment shows promising results in leukaemia trial

A new personalised treatment has been discovered for the most common form of adult leukaemia, which has been found to help patients live longer.
Vaccine in researcher hands

Can an immunisation technique speed up vaccine development?

Researchers in Germany have pioneered a system for displaying epitopes in mammal cells, potentially revolutionising immunisation studies.
Promoting regular exercise to protect brain health

Promoting regular exercise to protect brain health

Regular exercise is a critical step in maintaining healthy physiology and ensuring healthy aging. However, there are many diseases and conditions that make exercise inaccessible or reduce its efficacy. The Wessells lab studies exercise and the pathways it works through to identify key molecules required for a proper exercise response.
women in bed blowing nose with a cold

Which natural remedies will help you battle a cold this year?

With the days getting colder and colder and the flu season approaching, several health professionals give their insight and recommendations on natural remedies for illnesses.
Tissue from sellar lesion, microscopy show multiple wet keratin, basaloid appearing cells, inflammatory cells and giant cells. Diagnosis Craniopharyngioma.

Current and future therapy for BRAF-mutant pediatric glioma

Professor Peter J. Houghton from the Greehey Children’s Cancer Research Institute discusses new approaches to pediatric cancer treatment specifically for BRAF-mutant pediatric glioma.
Abs Lactobacillus Bulgaricus Bacteria’

Sepsis survivors: Improving long-term health outcomes post sepsis

Michael Wong and Amy Campbell from the Physician-Patient Alliance for Health & Safety reflect on the fourth World Sepsis Congress discussion, which focused on ways to improve long-term health outcomes post sepsis.

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