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The microbiome and aging: Unlocking new frontiers in healthy longevity

Research conducted by the USF Microbiomes Institute and the MiaGB Consortium is uncovering the significant link between microbial communities and host biology. This understanding could lead to new therapies for age-related conditions. Shalini Jain, Christian Brechot, and Hariom Yadav provide further insights.
image: © MissingSchool

Why “learn-from-anywhere” technology can help solve chronic school absence

Megan Gilmour, Churchill Policy and Deakin University Honorary Fellow, Australia, calls for legislation, technology, and policy to address complex school absence during medical or mental health challenges.
Closeup shot of an unrecognizable pregnant woman holding an ultrasound scan

Rethinking the reproductive clock: Can NAD+ preserve fertility?

Recent research indicates that the compound NAD+ offers a promising solution to support fertility and reproductive longevity.
Happy sitting and panting Golden retriever dog and blue Maine Coon cat looking at camera, Isolated on yellow stock photo

Amino acid nutrition: A vital foundation for canine and feline health

Elizabeth Morris, Ph.D. and Julia Guazzalli Pezzali, DVM, MS, Ph.D., emphasize that amino acid nutrition is a crucial foundation for the health of both dogs and cats.
Figure 1. Systemic immune responses elicited by oral dmLT-saponin combinations compared to injected vaccines (A) Cryo-electron microscopy (cryo-EM) image of the dmLT and saponin formulation demonstrating the formation of acid-stable micelle particles upon the addition of saponin to dmLT. (B) Preclinical evaluation of systemic serum IgG and IgA antibody responses following prime/boost vaccination. Antibody levels against the microbial protein antigen included in the vaccination were assessed two weeks post-final vaccination in immunized mice. Groups were stratified by vaccination route (intramuscular [IM] or sublingual [SL]) and adjuvant formulation (dmLT [D] and/or saponin [S]). Comparisons with unvaccinated controls (white bars) are shown. Statistical significance between groups is indicated (*P < 0.05), with the SL D+S group achieving the best IgG and IgA responses to vaccine antigen.

New strategies for an old problem – Oral vaccines research

Despite their advantages, oral vaccines encounter several challenges. Professor Elizabeth Norton from Tulane University discusses how her team is addressing these issues and their research on developing and testing dmLT and saponin combination adjuvants.
Figure 1: Key finding of the project is the SIS; using this system, you can consolidate the selection of soil health indicators.

AI4SoilHealth Science: Revolutionising soil health monitoring

Seasoned experts explain here the revolutionising of soil health monitoring through the science of the AI4SoilHealth project.
CC By 4.0. Adapted from original artwork by Rita Erven, GEOMAR/OceanNETs, ocean nourishment

Ocean nourishment sequestering carbon dioxide in the deep ocean

Phytoplankton have been essential to life on Earth for over 35 billion years. Through photosynthesis, they consume carbon dioxide on a scale comparable to that of forests and other land plants. Edwina Tanner from the WhaleX Foundation shares insights on this and discusses the potential for plankton-based solutions in marine carbon dioxide removal (mCDR) and ocean nourishment.

Teen relevant and open access health information for building vaccine confidence

With the abundance of health information about vaccines online, there is a need for an open educational resource (OER) that empowers youth to understand the importance of vaccines and make informed medical choices.
3d rendered image of firing neurons inside the human brain. Perfectly usable for biomedical topics or as a symbol for neural networks and artificial intelligence.

Role of extracellular electron transfer in the nitrogen cycle

Extracellular electron transfer impacts the nitrogen cycle by enhancing microbial processes and connecting to other biogeochemical cycles. Understanding EET mechanisms provides insights into ecosystem functioning and potential advancements; Arpita Bose and Zhecheng (Robert) Zhang explain.
Abstract polygonal brain with connected dots and lines. Artificial intelligence 3d illustration

Computational psychiatry and the opioid crisis: A deep dive

In this interview, we speak with Dr. Bo Cao, a leading expert in computational psychiatry at the University of Alberta, Canada. Dr. Cao discusses how advanced data analysis and machine learning are transforming our approach to the opioid crisis and mental health care, offering new hope in addressing one of North America’s most pressing public health challenges.
Figure 1: An active area of hay cultivation next to an abandoned area that was abandoned due to thaw subsidence and the formation of a pond at a farm in Fairbanks, AK. Note the elevation difference (>1 m) between the pond and the adjacent cultivated area.

Impacts of land clearing on areas containing permafrost

Melissa Ward Jones from the University of Alaska Fairbanks explores the impacts of land clearing on areas with permafrost.
FIGURE 1 shows the basic steps required to obtain genetic phase or haplotyping for the HLA system in a potential bone marrow transplant recipient without resorting to family studies. Studies to date have shown superior outcomes in haplotype-matched recipient/donor pairs compared to those matched for individual alleles at multiple HLA loci. (Kitcharoen, Petersdorf, Maskalana)

Single chromosome sequencing to obtain genetic phase (haplotyping)

Brian Tait, Chief Scientific Officer at Haplomic Technologies Pty Ltd, examines single chromosome sequencing to obtain genetic phase (haplotyping).
A new Mother sits in her baby's nursery with the infant in her arms and held to her chest, as she nurses him. She is dressed casually in a yellow t-shirt and looking down at the baby with a smile.

The hidden dangers of breastfeeding misconceptions: A deep dive

In the exclusive interview, Dr. Christie del Castillo-Hegyi, co-founder of the Fed is Best Foundation, sheds light on breastfeeding misconceptions and their devastating impact.
Software engineers working on project and programming in company. Startup business group working as team to find solution to problem. Woman programmer working on computer with colleagues standing by.

Gender stereotypes in technology startups

Professors Tonoyan, Strohmeyer, and Jennings explore how gender stereotypes shape job application intentions in emerging technology startups.

Decarbonising the textile industry: A revolutionary pigment from the lab to the market in...

Explore the journey of decarbonising the textile industry through the remarkable example of bringing a revolutionary pigment from the lab to the market in three years, starting with the milestones of this captivating journey.
Hand united together form lines, triangles and particle style design. Illustration vector

Top team effectiveness and how to develop it

Dr Michael (Mike) Beer, Professor Emeritus from Harvard Business School, explains top team effectiveness and how to develop it.
Cinchona (Cinchona officinalis). Called Fever tree also

A legacy of medicine and biodiversity: Protecting the cinchona tree

The endangered Cinchona officinalis, native to the Andean foothills, produced the world’s first anti-malarial drug. Augusta Cueva-Agila explains why it is crucial to conserve this species and how conservation efforts can be implemented.
Female Scientist Working in The Lab, Using Microscope

The European Cancer Pulse: From data intelligence to policy action

Norbert Couespel 1 and Mark Lawler 1, 2 highlight the European Cancer Pulse, a critical tool in tracking cancer inequalities and influencing cancer policy in Europe.
Hurricane rainfall flooded road. Drowned car on city street in Florida residential area. Consequences of hurricane natural disaster.

Climate change, water change and the critical role of community resilience

Dr. Amanda Shankland, Dr. Carolyn Johns, and Gail Krantzberg, explore climate change resilience, water change, and the critical role of climate-ready communities.
Figure 1. Comparison of prediction models in A) two-dimensional (2D) and B) three-dimensional (3D) analyses. The 2D model demonstrates a poor-fitting linear relationship constrained by limited variables. In contrast, the 3D model incorporates an additional dimension, providing a better fit and improved predictive accuracy. This highlights how multi-dimensional analysis, such as those enabled by machine learning, can uncover more complex relationships within heterogeneous clinical and biological data.

Predicting cochlear implant performance: Moving beyond single biomarkers and leveraging artificial intelligence

Matthew Shew, Amit Walia, and Craig A. Buchman highlight that the significant variability in speech perception among cochlear implant users can be addressed by using a multi- faceted approach that incorporates emerging technologies like machine learning and artificial intelligence to improve outcome prediction models.

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