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Shrouded in genomic heterochromatin are ancient viral-like elements that could jump
Host defences operate to prevent ‘ancient viruses’ from ever jumping but, in cancers, cells lose multiple layers of ‘epigenetic’ control, and this can lead to the awakening of jumping or ‘retrotransposition’ of ancient viruses.
Satellite DNA arrays barcode chromosomes to regulate genes
In this piece, Dr Helen Rowe summarizes how arrays or strings of multi-copy satellite DNAs can barcode chromosomes to regulate cell fate, by acting...
Unlocking dark matter in our genome to fuel immune responses
Dr Helen M Rowe at the Centre for Immunobiology at the Queen Mary University of London looks towards unlocking dark matter for the potential to boost immune responses in humans.
Unlocking dark matter for genome remodelling
Dr Helen Rowe, Senior Lecturer in Epigenetics, outlines the significance of research into dark matter and genome remodelling
