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Figure 1: Electrocochleography-total response (ECochG-TR) measured at the round window prior to cochlear implant insertion (RW-ECochG-TR) shows a weak correlation with performance in noise (AzBio +10 dB signal-to-noise ratio). Similarly, the MoCA score, a measure of cognitive function, also exhibits a weak correlation with performance in noise. However, a multivariate model incorporating both cochlear health (ECochG-TR), cognition (MoCA score), and their interaction (product of ECochG-TR and MoCA) explains 46.0% of the variability in noise performance. This finding suggests that while good cochlear health is necessary for strong performance in noise, it is not sufficient on its own – it must be complemented by adequate cognitive function.

Cognitive function and electrode mapping’s role in cochlear implant performance

Amit Walia, Matthew Shew and Craig A. Buchman from Washington University School of Medicine, detail the role of cognitive function and electrode mapping in cochlear implant performance.
Wireframe of the internal structure of the human ear. 3D. Front view. Vector illustration.

Glutamate excitotoxicity in the cochlea

Mark Rutherford, Associate Professor at Washington University School of Medicine, discusses the burden and causes of hearing dysfunction, as well as the possible solutions for mitigating glutamate excitotoxicity.

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