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Cellular scaffolding: Crowdsourcing cellular responses in health and disease
In this article, Dr Alan Herbert discusses how different types of cellular scaffolds interact and impact the risk of diseases, citing the example of Z-RNAs pushing cells to inflammatory states in tumors and autoimmune conditions, setting the stage for new therapeutics.
Flipons: The discovery of Z-DNA and soft-wired genomes
Alan Herbert, Founder and President of InsideOutBio, discusses alternative DNA conformations and understanding of their biological functions.
InsideOutBio.com: New pathways to overcome tumor-induced suppression
InsideOutBio is focused on the immunotherapy of cancers, exploiting newly discovered pathways to overcome tumor-induced suppression of host immune responses.
RNA and DNA flipons in health and disease
Flipons are the next step in DNA research. What they are, their role in DNA and RNA coding, their impact on medical science, and their relation to the immune system are discussed here.