DNA

Harnessing genomic data for early disease detection

Lorna Rothery spoke to Heidi Rehm, Chair of the Global Alliance for Genomics and Health, about steps to harness quality genomic data to support disease detection and the importance of collaboration in this endeavour.

How do environmental factors affect foetal development?

Associate Professor Ken Tachibana, discloses how prenatal ambient fine particle exposure disrupts DNA methylation and subsequent gene expression in the foetal development stage.

Ground-breaking technology: Next generation sequencing

Cecilia Van Cauwenberghe from Frost & Sullivan’s TechCasting Group, provides a portrait of a ground-breaking technology, next-generation sequencing, starting with a brief snapshot.

Next-generation sequencing to analyse biological tissues

Richie Kohman, Synthetic Biology Platform Lead at Wyss Institute at Harvard, explains the use of next-generation sequencing to analyse biological tissues in a spatially resolved context.

Application of ‘click chemistry’ ligation techniques to modified DNA and RNA

Professor Afaf El-Sagheer and Professor Tom Brown from the Department of Chemistry, Suez University and Oxford University describe their research, including the application of ‘click chemistry’ conjugation techniques to DNA.

Deep ocean drilling: Revealing earth history, geological processes and a deep biosphere

Virginia Edgcomb from the Woods Hole Oceanographic Institution discusses deep ocean drilling, a process that reveals earth history, geological processes and a deep biosphere.

Researchers discover marine fish DNA from 300 years ago

Ehime University researchers used samples from Japan to test if marine fish DNA existed in the same place for the last 300 years.

Single-cell genomics: Clinical strategies for COVID-19

Here, Cecilia Van Cauwenberghe from Frost & Sullivan’s TechVision Group argues that single-cell genomics empowers clinical strategies for COVID-19.

Machine learning will help to grow artificial organs

Researchers in Moscow and America have discovered how to use machine learning to grow artificial organs, especially to tackle blindness.

Gyrase and topoisomerase IV: Repurposing old targets for new antibacterials

Neil Osheroff from the Vanderbilt University School of Medicine is working to overcome drug resistance and revitalise the use of established targets for antibacterial agents, as we discover here.

Elucidating the pathogenesis of paediatric cancers

Prof Nicolo Riggi and Prof Ivan Stamenkovic from the University of Lausanne share their thoughts on the pathogenesis of paediatric cancers.

Plant pathology: The global impact of wheat diseases

Dr Kim Hammond-Kosack at Rothamsted Research highlights an aspect of plant pathology that concerns the importance of finding new ways to disarm old enemies in wheat diseases.

Researchers create world’s most detailed map of breast cancer risk

An international team identified over 350 DNA 'errors' that increase risk of developing the disease, creating a map of breast cancer risk.

Bringing mathematical perspectives to the biological search for the Rules of Life

Editor of Open Access Government, Jonathan Miles, spoke to Juan Meza at the National Science Foundation about the launch of four new centres to bring mathematical perspectives to the biological search for the Rules of Life.

Cancer: Breakthrough technologies allowing leveraging biomarkers for oncology

Cecilia Van Cauwenberghe from Frost & Sullivan’s TechVision Group, provides a cancer focus, in particular, she details breakthrough technologies that allow leveraging biomarkers for oncology.

Synthetic biology: Past, present and future

Gábor Balázsi, Ph.D. from the Louis and Beatrice Laufer Center for Physical and Quantitative Biology and the Department of Biomedical Engineering at Stony Brook University in the U.S., shares his perspective on the field of synthetic biology in terms of the past, present and future.

Paediatric Hepatitis B: Investigating fingernails and hair

Here, Haruki Komatsu discusses how Paediatric Hepatitis B virus (HBV) infection is one of the main things which can lead to liver cirrhosis and hepatocellular carcinoma.

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