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Drug Development

iDOMO: New AI tool predicts synergistic drug combinations

Researchers at Mount Sinai have developed iDOMO, a powerful AI tool that predicts synergistic drug combinations for complex diseases like cancer.

Moderna and Pfizer vaccines 90% effective in US real-world data

Real-world use of the Moderna and Pfizer vaccines in the United States reveals that both are working at 90% efficacy - with data pointing to one dose being capable of 80% protection.

Biosimilars: Improve access to treatment & reduce cost

Tore K Kvien & Guro L Goll argue that biosimilars are an opportunity for improving access to treatment & reducing cost and provide comment on the NOR-SWITCH study.

Data finds 36% of people refuse COVID vaccine due to side effect fears

According to new ONS data, 36% of UK people who are vaccine hesitant have strong side effect fears - while a further 12% fear needles, and 22% think vaccines could impact fertility.

CBD Novel Foods in the UK

Lead Scientific Officer at Always Pure Organics Andrew Megahy, explains how the UK is now in a prime position for the future of CBD use, due to the Novel Foods Application.

AstraZeneca vaccines made for UK could be kept for EU use only

EU leaders today (25 March) decided not to create an export ban for AstraZeneca vaccines made for the UK - but the feud between AstraZeneca and the bloc remains close to the surface of future discussions.

Dexamethasone steroid saved one million people from COVID death

The Dexamethasone steroid has been used across the globe to help treat COVID-19 in the ICU - leading to atleast one million survivors of hospitalisation from the virus.

US trial finds AstraZeneca vaccine 100% effective against COVID death

In a study of over 32,000 people, a US trial found the AstraZeneca vaccine was 100% effective against deaths caused by COVID-19 - the vaccine did not show any connection to blood clots.

Polymers and polymer-based drug delivery in the treatment of dry eye disease

Professor Heather Sheardown, C20/20 Ophthalmic Materials Innovation Hub, Department of Chemical Engineering, McMaster University, explores how polymers can be used to treat dry eye disease.

European Medicines Agency say AstraZeneca does not cause blood clots

The safety committee of the European Medicines Agency said the investigation did not prove that AstraZeneca vaccinations cause blood clots - describing the possibility as an "extremely small likelihood".

European Commission says vaccine deliveries to UK could be stopped

President von der Leyen today (17 March) said that the Commission would limit vaccine deliveries to the UK if "the situation does not change" - suggesting that the drugmaker AstraZeneca is responsible for vaccination delays in the EU.

Birth control creates higher risk of blood clots than AstraZeneca vaccine

Currently, several EU countries are suspending use of the AstraZeneca vaccine due to reports of blood clot risks - in response, people are speaking out about the higher risk of blood clots posed by contraceptive pills used globally.

How global evidence can improve outcomes for spinal patients

Everard Munting, President of EUROSPINE, explains why sharing knowledge about spinal treatments on a global scale is the most effective way to develop best practice and enable early interventions.

European Medicines Agency says AstraZeneca vaccine still safe to use

Over the weekend, the Republic of Ireland suspended their use of AstraZeneca due to reports of blood clots in Norway - in response, the European Medicines Agency (EMA) says the AstraZeneca vaccine is still safe to use.

Diphtheria slowly becomes resistant to antimicrobial treatment

There is a well-established diphtheria vaccine taken by millions of people, but researchers are now observing the disease evolving a resistance to antimicrobial treatment.

Novavax 96.4% effective against the original COVID mutation

The US based vaccine appears to be 96.4% effective against the original COVID mutation, with 86% efficacy against the UK variant and only 55% against the South African variant.

How valuable are randomised controlled trials in reproductive medicine?

Professor Darren Griffin reflects on how patients in fertility clinics should interpret the scientific evidence base when even the experts can’t seem to agree.

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